Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3867 | Ajmaline |
| 1. Ajmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. 2. Ajmaline inhibits cardiac Kv1.5 and Kv4.3 channels at therapeutic concentrations. | |
| BCN3868 | Desmethylbellidifolin |
| 1. Desmethylbellidifolin shows stronger antioxidative properties than those of butylated hydroxytoluene (BHT) and α-tocopherol. 2. Desmethylbellidifolin exhibits at the dose of 200 ug/disk a significant inhibition of the growth of Staphylococcus aureus. 3. Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method. | |
| BCN3869 | Alliin |
| 1. Alliin protects against Lipopolysaccharides (LPS)-induced acute lung injury (ALI) by activating PPARγ, which subsequently inhibits LPS-induced NF-κB activation and inflammatory response, alliin may be used as an anti-inflammatory agent in the treatment of ALI. 2. Alliin has antiglycating potential , it offers protection against glucose or methyglyoxal induced glycation of superoxide dismutase. 3. Alliin has a good antiglycating effect and hence is expected to have therapeutic potential in the prevention of glycation-mediated diabetic complications. 4. Alliin and sabinene have detectable levels of antimicrobial activity. 5. Alliin has an inhibitory effect in osteoclasteogenesis with a dose-dependent manner via blocking the c-Fos-NFATc1 signaling pathway, it could be a potential therapeutic agent in the treatment of osteoporosis. | |
| BCN3870 | Ranaconitine |
| Ranaconitine has cardiotoxicity. | |
| BCN3873 | 25S-Inokosterone |
| 1. 25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells, they have excellent anti-atopy activity, thus they could be used to a large range of functional anti-atopy cosmetics. | |
| BCN3874 | 25R-Inokosterone |
| 1. 25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells, they have excellent anti-atopy activity, thus they could be used to a large range of functional anti-atopy cosmetics. | |
| BCN3875 | Cratoxylone |
| 1. Cratoxylone exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with the IC₅₀ value belows 3 uM. | |
| BCN3876 | Perillyl alcohol |
| Perillyl alcohol has potential chemopreventive, and antileukemia activities, it can suppress antigen-induced immune responses in the lung, it could be a novel preventive or therapeutic option for immunologic lung disorders such as asthma with minimal side effects. Perillyl alcohol can suppress antigen-induced immune responses in the lung, it could be a novel preventive or therapeutic option for immunologic lung disorders such as asthma with minimal side effects. | |
