(±)-1-(1,2-Diphenylethyl)piperidine maleateCAS# 207461-99-2 |
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Quality Control & MSDS
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| Cas No. | 207461-99-2 | SDF | Download SDF |
| PubChem ID | 57369670 | Appearance | Powder |
| Formula | C23H27NO4 | M.Wt | 381.47 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 10 mM in water | ||
| Chemical Name | but-2-enedioic acid;1-(1,2-diphenylethyl)piperidine | ||
| SMILES | C1CCN(CC1)C(CC2=CC=CC=C2)C3=CC=CC=C3.C(=CC(=O)O)C(=O)O | ||
| Standard InChIKey | AEHZEDLXDLPQQD-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C19H23N.C4H4O4/c1-4-10-17(11-5-1)16-19(18-12-6-2-7-13-18)20-14-8-3-9-15-20;5-3(6)1-2-4(7)8/h1-2,4-7,10-13,19H,3,8-9,14-16H2;1-2H,(H,5,6)(H,7,8) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | High affinity antagonist at the ion channel on the NMDA receptor. |
(±)-1-(1,2-Diphenylethyl)piperidine maleate Dilution Calculator
(±)-1-(1,2-Diphenylethyl)piperidine maleate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6214 mL | 13.1072 mL | 26.2144 mL | 52.4288 mL | 65.536 mL |
| 5 mM | 0.5243 mL | 2.6214 mL | 5.2429 mL | 10.4858 mL | 13.1072 mL |
| 10 mM | 0.2621 mL | 1.3107 mL | 2.6214 mL | 5.2429 mL | 6.5536 mL |
| 50 mM | 0.0524 mL | 0.2621 mL | 0.5243 mL | 1.0486 mL | 1.3107 mL |
| 100 mM | 0.0262 mL | 0.1311 mL | 0.2621 mL | 0.5243 mL | 0.6554 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines.[Pubmed:7504360]
Trends Pharmacol Sci. 1993 Sep;14(9):325-31.
NMDA and non-NMDA (AMPA/kainate) antagonists have potential in the treatment of a diverse group of neurological disorders associated with excessive activation of excitatory amino acid receptors. Here Michael Rogawski reviews recent progress in the development of therapeutically useful NMDA receptor channel blockers and a new class of selective AMPA/kainate receptor antagonists, the 2,3-benzodiazepines. Research on these novel noncompetitive excitatory amino acid antagonists has opened promising new avenues for the development of drugs to treat epilepsy, ischaemia, neurodegeneration and Parkinson's disease.
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