Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3352 | 4-O-Feruloylquinic acid |
| 4-O-Feruloylquinic acid can be useful for the prevention of cardiovascular and other chronic diseases. | |
| BCN3353 | 3-O-Feruloylquinic acid |
| 1. 3-O-Feruloylquinic acid is a protease inhibitor. 2. 3-O-Feruloylquinic acid exerts moderate inhibitory effect against AIV (H5N1) in vitro. | |
| BCN3357 | 1,3,5-Trihydroxyxanthone |
| 1. 1,3,5-Trihydroxyxanthone has selective inhibitory activity on platelet aggregation induced by adenosine diphosphate. | |
| BCN3360 | Alisol F |
| 1. Alisol F suppresses iNOS induction. 2. Alisol F and 25-Anhydroalisol F show anti-inflammatory activities and liver protection through the inhibition of MAPK, STAT3, and NF-κB activation in vitro and in vivo. 3. Alisol F exhibits inhibitory effects on lipopolysaccharide-induced NO production in RAW 264.7 macrophage cells. 4. Alisol F exhibits inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the Hep G2.2.15 cell line with the IC (50) value of 0.6 microM, and on HBV e antigen (HBeAg) secretion with the IC (50) value of 8.5 microM. | |
| BCN3361 | 25-Anhydroalisol F |
| 1. 25-Anhydroalisol F shows anti-inflammatory activities and liver protection through the inhibition of MAPK, STAT3, and NF-κB activation in vitro and in vivo. 3. 25-Anhydroalisol F exhibits inhibitory effects on lipopolysaccharide-induced NO production in RAW 264.7 macrophage cells. | |
| BCN3364 | Alisol B |
| 1. Alisol B can suppress C3a induced epithelial-mesenchymal transition . 2. Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. 3. Alisol B also inhibited RANKL-induced expression of NFATc1 and c-Fos, which are key transcription factors for osteoclastogenesis. 4. The molecular target of Alisol B is the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase, it provides detailed insights into the cytotoxic mechanism of a novel antitumor compound. | |
| BCN3367 | Norjuziphine |
| 1. Norjuziphine has antiplatelet aggregation activity. | |
| BCN3369 | Trimethylgallic acid methyl ester |
| Trimethyl gallic acid methyl ester shows superior antioxidant activity (IC50<100 uM). | |
