Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1521 - 1528 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5920 | PLP (139-151) |
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Synthetic myelin proteolipid protein (PLP) fragment. Immunization with this peptide induces severe clinical and histological experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis.
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| BCC5921 | CGP 42112 |
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Selective, high affinity angiotensin AT2 receptor ligand (Ki = 0.24 nM). Displays agonistic properties at proximal tubule AT2 receptors, causes Na+, K+-ATPase inhibition and sodium excretion. Antagonizes Ang-II induced contractions in rabbit aortic rings (IC50 = 1850 nM).
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| BCC5922 | JMV 390-1 |
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Inhibitor of the major neurotensin and neuromedin N degrading enzymes (IC50 values are 31, 40, 52 and 58 nM for endopeptidase 24.15, endopeptidase 24.11, leucine aminopeptidase and endopeptidase 24.16 respectively). Exhibits analgesic effects in various nociception assays.
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| BCC5923 | Hemokinin 1 (human) |
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Endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.
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| BCC5924 | CFM 1571 hydrochloride |
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Soluble guanylyl cyclase (sGC) activator (EC<sub>50</sub> = 5.49 <span class='symbol'>μ</span>M). Does not activate adenylyl cyclase, shows no significant inhibition of phosphodiesterases and displays minimal inhibition of iNOS (25%) and nNOS (17%). Inhibits collagen-stimulated platelet aggregation <em>in vitro</em> (IC<sub>50</sub> = 2.84 <span class='symbol'>μ</span>M).
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| BCC5925 | DOI hydrochloride |
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Brain penetrant, mixed 5-HT<sub>2A</sub>/5-HT<sub>2C</sub> receptor agonist (K<sub>i</sub> values are 0.7, 2.4 and 20 nM for 5-HT<sub>2A</sub>, 5-HT<sub>2C</sub> and 5-HT<sub>2B</sub> receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT<sub>2A</sub> receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)-<span class='symbol'>α</span>.
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| BCC5926 | Locustatachykinin I |
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Insect tachykinin-related peptide (TRP) isolated from Locusta migratoria. Exhibits sequence homology with vertebrate tachykinins.
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| BCC5927 | Dexfenfluramine hydrochloride |
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Indirectly agonizes serotonin receptors via inhibition of 5-HT re-uptake and stimulation of 5-HT release. Anorectic agent; decreases growth hormone, insulin, leptin, fat mass, lean mass and increases ghrelin in diet-switched diet-induced obese mice.
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