Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN3306 Pallidol
Pallidol is a potent and selective singlet oxygen quencher in aqueous systems, it may be used in singlet oxygen-mediated diseases as a pharmacological agent.
BCN3308 Leachianone G
1. Leachianone G shows inhibitory activities against pancreatic lipase, it may be used as drug candidate to control obesity. 2. (+/-)Leachianone G 1b, bearing 8-prenyl and 2',4'-dihydoxyl groups, exhibits potent vasorelaxant and neuroprotective effects. 3. Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays. 4. Leachianone G shows potent antiviral activity (IC(50) = 1.6 microg/ml).
BCN3311 8-Prenylkaempferol
1. 8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction. 2. 8-Prenylkaempferol induces differentiation/maturation of MC3T3-E1 osteoblasts by BMP-2/p38/Runx2 pathways , might be a promising agent for inducing osteogenesis. 3. 8-Prenylkaempferol might be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and IRF-3 and in part by interfering with IκB degradation which subsequently decreases NF-κB translocation.
BCN3316 Schisandrone
1. Schisandrone can suppress the Aβ-induced oxidative stress and inflammatory reaction through influencing NF-κB signaling pathway, exerting its protective effect on Alzheimer disease. 2. Schisandrone has strong activities of anti-oxidation, effectively scavenges hydroxyl radical and superoxide anion, and has protective effects on cells under active oxygen stress state. 3. Schisandrone can significantly decrease phosphorylation levels of Tau protein at 396, 262 sites, and relieve neuronal injury, but the phosphorylation level does not reach a negative cell level.
BCN3317 Atanine
1. Atanine possesses anthelmintic and antiparasitic activities.
BCN3320 Deapi-platycoside E
1. Deapi-platycoside E maybe have anti-HCV activity.
BCN3321 Lobetyol
1. Lobetyol exhibits DPPH radical scavenging activity. 2. Lobetyol and Lobetyolin show significant antioxidant activity.
BCN3322 Lobetyolinin
1. Lobetyolinin exhibits DPPH radical scavenging activity.