Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1545 - 1552 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5945 | BIM 23052 |
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Somatostatin sst5 receptor agonist (Ki values are 7.3, 13.5, 31.3 and 141 nM for sst5, sst2, sst1 and sst4 receptors respectively). Stimulates gastric emptying following i.c. administration.
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| BCC5946 | HU 211 |
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NMDA antagonist (IC<sub>50</sub> = 11 <span class='symbol'>μ</span>M for inhibition of [<sup>3</sup>H]MK-801 binding to rat forebrain membranes). Protects against NMDA- and quisqualate-induced neurotoxicity (EC<sub>50</sub> = 3.8 <span class='symbol'>μ</span>M) and enhances dopamine D<sub>1</sub> receptor activity. Inhibits NF-<span class='symbol'>κ</span>B, reducing TNF-<span class='symbol'>α</span>, IL-6 and nitric oxide production, and acts as a free radical scavenger. Exhibits beneficial effects in experimental models of multiple sclerosis, bacterial meningitis, septic shock, epilepsy, and traumatic and ischemic brain injury. Brain penetrant.
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| BCC5947 | DOB hydrochloride |
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Selective 5-HT2 receptor agonist (Ki values are 0.44, 59, 69, 831 and 3700 nM for 5-HT2H, 5-HT2L, 5-HT2C, 5-HT1B and 5-HT1A receptors respectively). Hallucinogenic.
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| BCC5948 | SC 58125 |
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Selective cyclooxygenase 2 (COX-2) inhibitor (IC<sub>50</sub> values are 0.04 and >100 <span class='symbol'>μ</span>M for COX-2 and COX-1 respectively). Anti-inflammatory; blocks edema and hyperalgesia <em>in vivo</em> following an inflammatory insult, without causing gastric mucosal damage. Also displays antitumor activity.
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| BCC5949 | SB 242084 |
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5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity.
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| BCC5950 | NPE-caged-HPTS |
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Caged fluorescent pH indicator. Rapidly releases the fluorophore HPTS (pyranine) (pKa 7.25) upon two-photon excitation (>3000 s-1). Routinely used for photolysis calibration. Suitable for use in small-compartment diffusion studies.
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| BCC5951 | PEPA |
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Novel allosteric potentiator of AMPA receptor desensitization. Slows the rate of onset of desensitization and potentiates steady-state equilibrium currents induced by glutamate with subunit (GluA3/4 > GluA1) and splice variant (flop > flip) selectivity. Ameliorates post-ischemic memory impairment in rats following i.v. administration.
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| BCC5952 | SNX 482 |
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Potent and selective, voltage-dependent R-type Ca<sub>V</sub>2.3 calcium channel blocker (IC<sub>50</sub> = 30 nM). Antinociceptive; inhibits nociceptive C-fibre and A<span class='symbol'>δ</span>-fibre-evoked neuronal responses.
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