Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC2448 | 4-HQN |
| 1. Some 4-quinazolinone derivatives have antiplatelet activity. | |
| BCN8032 | Desoxypeganine |
| 1. Desoxypeganine is being developed for its potential utility in the pharmacological treatment of alcohol abuse to reduce craving and depression in alcohol abusers, and might also be useful as a smoking cessation aid. 2. Desoxypeganine is a cholinesterase inhibitor, acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B. | |
| BCN8031 | 5'-Methoxynobiletin |
| 1. 5'-Methoxynobiletin may exhibit antinociceptive and anti-inflammatory activities in both formalin phases. | |
| BCN8030 | 5,7-dimethoxy-2,2-dimethylchromene |
| 1. 5,7-Dimethoxy-2,2-dimethylchromene is a potential inhibitor of juvenile hormone onLocusta migratoria. | |
| BCN8027 | 3,4,5-Tri-O-galloylquinic acid |
| 1. 3,5-Dicaffeoyl-epi-quinic acid shows anti-inflammatory activity, it may improve mast cell-mediated inflammatory diseases. | |
| BCN6427 | Fucosterol |
| 1. Fucosterol has anti-diabetic activity in vivo, it exhibits an inhibition of sorbitol accumulations in the lenses and causes an inhibition of blood glucose level and glycogen degradation. 2. Fucosterol possesses anti-oxidant and hepatoprotective activities . 3. Fucosterol shows cytotoxic effect against breast and colon carcinoma cell lines. 4. Fucosterol exhibits anti-inflammatory activity which might attribute to inhibition of NO and ROS generation and suppression of the NF-κB pathway. 5. Fucosterol is a dual-LXR agonist that regulates the expression of key genes in cholesterol homeostasis in multiple cell lines without inducing hepatic triglyceride accumulation. 6. Fucosterol has antihistaminic, anticholinergic and antiviral activities. 7. Fucosterol could as an anti-obesity agent, it can inhibit expression of PPARγ and C/EBPα, resulting in a decrease of lipid accumulation in 3T3-L1 pre-adipocytes. | |
| BCN8020 | Chloranthalactone B |
| 1. Chloranthalactone B has anti-inflammatory activity, it inhibits the production of inflammatory mediators by inhibiting the AP-1 and p38 MAPK pathways. | |
| BCN8019 | Hulupinic acid |
| 1. Hulupinic acid may show inhibitory activities on the production of NO in macrophage RAW 264.7 cells. | |
