Uralenol

CAS# 139163-15-8

Uralenol

Catalog No. BCN7994----Order now to get a substantial discount!

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Uralenol: 5mg Please Inquire In Stock
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Quality Control of Uralenol

Number of papers citing our products

Chemical structure

Uralenol

3D structure

Chemical Properties of Uralenol

Cas No. 139163-15-8 SDF Download SDF
PubChem ID 5315126 Appearance Powder
Formula C20H18O7 M.Wt 370.35
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-[3,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-3,5,7-trihydroxychromen-4-one
SMILES CC(=CCC1=C(C(=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O)C
Standard InChIKey WOMWVGHYSNATOB-UHFFFAOYSA-N
Standard InChI InChI=1S/C20H18O7/c1-9(2)3-4-10-5-11(6-14(23)17(10)24)20-19(26)18(25)16-13(22)7-12(21)8-15(16)27-20/h3,5-8,21-24,26H,4H2,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Uralenol

The roots of Glycyrrhiza uralensis

Biological Activity of Uralenol

Description1. Uralenol significantly shows the inhibitory activities against the PTP1B enzyme. 2. Uralenol shows inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate(IC50 =49.5 uM). 3. Uralenol shows potent anti-proliferation effects on ER-positive breast cancer MCF-7 cells in vitro.
TargetsTyrosinase | Estrogen receptor | Progestogen receptor

Uralenol Dilution Calculator

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Uralenol Molarity Calculator

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Preparing Stock Solutions of Uralenol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7001 mL 13.5007 mL 27.0015 mL 54.003 mL 67.5037 mL
5 mM 0.54 mL 2.7001 mL 5.4003 mL 10.8006 mL 13.5007 mL
10 mM 0.27 mL 1.3501 mL 2.7001 mL 5.4003 mL 6.7504 mL
50 mM 0.054 mL 0.27 mL 0.54 mL 1.0801 mL 1.3501 mL
100 mM 0.027 mL 0.135 mL 0.27 mL 0.54 mL 0.675 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Uralenol

Natural PTP1B inhibitors from Broussonetia papyrifera.[Pubmed:12419367]

Bioorg Med Chem Lett. 2002 Dec 2;12(23):3387-90.

Two new compounds, 8-(1,1-dimethylallyl)-5'-(3-methylbut-2-enyl)-3',4',5,7-tetrahydroxyflanvonol (1), 3'-(3-methylbut-2-enyl)-3',4',7-trihydroxyflavane (2) and three known compounds 3,3',4',5,7-pentahydroxyflavone (3), Uralenol (4), broussochalcone A (5) were isolated from the roots of Broussonetia papyrifera, and their structures determined by spectroscopic methods. Compounds 1, 3, 4 and 5 significantly show the inhibitory activities against the PTP1B enzyme.

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