Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7812 | 8-Epidiosbulbin E acetate |
| 1. 8-Epidiosbulbin E acetate exhibits time-and dose-dependent liver injury in mice. 2. 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci. | |
| BCN2954 | Desoxyrhaponticin |
| Desoxyrhaponticin is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes. Desoxyrhaponticin could be considered as a promising fatty acid synthase(FAS) inhibitor, it could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. | |
| BCN7818 | Chicanine |
| 1. Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways. 2. Chicanine has good anti-proliferation (IC₅₀=44.2uM) on prostate cells and antioxidant activities (IC₅₀=26.0 uM,) with no significant toxic effects on normal cells. | |
| BCN2955 | Tubeimoside II |
| Tubeimoside I, tubeimoside II, and tubeimoside III show anti-inflammatory, antitumor, and antitumor-promo ting effects. | |
| BCN2956 | Tubeimoside III |
| Tubeimoside III has anti-inflammatory, anti-tumor, and anti-tumorigenic activities, stronger than those of tubeimoside II. It has acute toxicity, stronger than that of tubeimoside II. | |
| BCN7819 | Timosaponin AI |
| 1. Timosaponin AI can inhibit dipeptidyl peptidase-4 (DPP-4) activity in a dose-dependent manner, the DPP-4 inhibitor has been clinically used for the treatment of type 2 diabetes mellitus. | |
| BCN2957 | Cephalotaxine |
| Cephalotaxine is an antiviral as well as antitumor agent. It is useless for the treatment of infection by flaviviruses, but potentially useful in combined therapy against hepatitis B. | |
| BCN2958 | 5-O-Demethylnobiletin |
| 5-O-Demethylnobiletin has anti-inflammatory activity, it may act through a direct inhibition of 5-LOX, without affecting the expression of COX-2. | |
