Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1129 - 1136 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5200 | SB-334867 free base |
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Selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.
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| BCC5202 | Y-320 |
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Y-320 is an orally active immunomodulator and inhibitor of IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20 to 60 nM.
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| BCC5203 | VGX-1027 |
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Orally active immunomodulatory agent that primarily targets macrophages. Inhibits TNF-<span class='symbol'>α</span> secretion via interference of macrophage toll-like receptor (TLR) 4 and TLR 2/6 signaling pathway. Also reduces the secretion of pro-inflammatory cytokines IL1-<span class='symbol'>β</span>, IL-10 and IFN-<span class='symbol'>γ</span>. Antidiabetogenic; prevents IL-<span class='symbol'>β</span> and IFN-<span class='symbol'>γ</span>-induced pancreatic islet cell death <em>in vitro</em>.
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| BCC5210 | Procaine |
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Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. It is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells, it inhibits the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells.
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| BCC5214 | Nicergoline |
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<span class='symbol'>α</span>-adrenergic, vasodilator. Cognitive enhancer.
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| BCC5215 | Buprenorphine hydrochloride |
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ORL<sub>1</sub> receptor agonist that also displays mixed antagonist/partial agonist activity at <span class='symbol'>κ</span>, <span class='symbol'>δ</span> and <span class='symbol'>μ</span>-opioid receptors.
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| BCC5217 | Tiagabine hydrochloride |
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GABA uptake inhibitor (IC50 = 67 nM in vivo). Exhibits high affinity and selectivity for the GAT-1 GABA transporter. Anticonvulsant; also attenuates established dynorphin-induced allodynia in a mouse model after systemic administration.
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| BCC5224 | Dihydroergotamine mesylate |
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Partial <span class='symbol'>α</span>-adrenergic agonist. Partial D<sub>2</sub> dopaminergic receptor agonist. Competitive 5-HT antagonist.
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