Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1073 - 1080 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5037 | Clozapine |
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Atypical antipsychotic drug, with a much lower tendency to cause extrapyramidal side effects than conventional neuroleptics. Displays a broad range of pharmacological actions; the antipsychotic effects are thought to be mediated principally by 5-HT<sub>2A/2C</sub> and dopamine receptor blockade (K<sub>i</sub> values are 21, 170, 170, 230 and 330 nM for D<sub>4</sub>, D<sub>3</sub>, D<sub>1</sub>, D<sub>2</sub> and D<sub>5</sub> receptors respectively).
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| BCC5039 | Eletriptan HBr |
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Orally active, selective 5-HT1B/1D receptor agonist. Produces a dose-dependent reduction in carotid artery blood flow in vivo. Displays antimigraine activity.
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| BCC5040 | Escitalopram Oxalate |
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Selective 5-HT reuptake inhibitor (K<sub>i</sub> values are 0.89, 8150, and 10500 nM for serotonin, noradrenalin, and dopamine transporters respectively). Is a <em>S</em>-enantiomer and eutomer of citalopram.
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| BCC5042 | Olanzapine |
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Antagonist of 5-HT<sub>2A</sub> and dopamine D<sub>2</sub> receptors (K<sub>i</sub> values are 4 and 11 nM respectively). Also displays affinity for a range of other receptors including D<sub>1</sub> and D<sub>4</sub>, 5-HT<sub>2C</sub>, <span class='symbol'>α</span><sub>1</sub>, H<sub>1</sub> and M<sub>1-4</sub> receptors (K<sub>i</sub> values range between 1.9 and 31 nM) . Atypical antipsychotic. Displays anticholinergic properties.
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| BCC5044 | Urapidil HCl |
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<span class='symbol'>α</span><sub>1</sub>-adrenoceptor antagonist and 5-HT<sub>1A</sub> receptor agonist (pIC<sub>50</sub> values are 6.13 and 6.4 respectively). Clinically used hypotensive agent.
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| BCC5046 | Atomoxetine HCl |
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Potent and selective noradrenalin re-uptake inhibitor (K<sub>i</sub> values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Displays minimal affinity for a range of other neurotransmitter receptors and transporters (K<sub>i</sub> > 1 <span class='symbol'>μ</span>M). Antidepressant.
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| BCC5047 | BRL-54443 |
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A potent 5-ht<sub>1E/1F</sub> receptor agonist (pEC<sub>50</sub> values are 8.5 and 8.6 respectively). Displays > 30-fold selectivity over other 5-HT and dopamine receptors (pK<sub>i</sub> values are 8.7. 8.9, 7.2, 6.9, 7.2, 5.9, 7.0, 6.5, < 6, < 6, 6.3 and 6.2 for human 5-HT<sub>1E</sub>, <sub>1F</sub>, <sub>1A</sub>, <sub>1B</sub>, <sub>1D</sub>, <sub>2A</sub>, <sub>2B</sub>, <sub>2C</sub>, <sub>4</sub>, <sub>7</sub>, D<sub>2</sub> and D<sub>3</sub> receptors respectively). Induces 5-HT<sub>2A</sub> receptor-mediated mouse aortic contraction <em>in vitro</em> (pEC<sub>50</sub> = 6.52). Active <em>in vivo</em>.
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| BCC5048 | Desvenlafaxine Succinate |
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Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
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