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Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No.	Product Name
BCN2892	(2S)-Isoxanthohumol
1. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic properties, seems to regulate in vivo vascular proliferation and stabilization and the EC-VSMC-inflammatory crosstalk.
BCN6376	Deoxytrillenoside A
1. The combination of Cochinchinenin A, cochinchinenin B, and loureirin B is the material basis for the analgesic effect of Dragon’s Blood.
BCN2893	Tenuifoliside A
Tenuifoliside A has anti-apoptotic,neuroprotective,and anti-inflammatory effects, it inhibits the NF-κB and MAPK pathways.
BCN2894	Bruceine D
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
BCN2896	Soyasaponin Ab
1. Soyasaponin Ab has anti-inflammatory effects, it can inhibit colon shortening, myeloperoxidase activity, the expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), and activation of the transcription factor nuclear factor-κB (NF-κB); soyasaponin Ab (1, 2, 5, and 10 μM) can inhibit the production of NO (IC50 = 1.6 ± 0.1 uM) and prosta. 2. Soyasaponin Aa and Ab can markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα in 3T3-L1 adipocytes. 3. Soyasaponins Ab and Bb can prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase, exhibit memory-enhancing effects. 4. Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab.
BCN2897	Soyasaponin Ac
1. Soyasaponins have chemoprevention activities, they prevent H2O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells. 2. Soyasaponins can significantly decrease blood glucose, improve atherosclerotic index, and inhibit lipid peroxidation and platelet aggregation in diabetic rats, which may be useful in prevention and control of diabetes mellitus and diabetes-associated atherosclerosis. 3. Soyasaponins abundant in soybean have anti-inflammatory activities, low-dose SSs alleviated contact hypersensitivity (CHS) symptoms by attenuating inflammation and improving the intestinal microbiota composition, suggesting that dietary SSs may have beneficial effects on allergic contact dermatitis (ACD). 4. Dietary soyasaponin has inhibitory effects on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice.
BCN6389	Lucidenic acid L
1. Soyasaponins has chemoprevention activities, it prevent H₂O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells. 2. Soyasaponins can significantly decrease blood glucose, improve atherosclerotic index, and inhibit lipid peroxidation and platelet aggregation in diabetic rats, which may be useful in prevention and control of diabetes mellitus and diabetes-associated atherosclerosis. 3. Soyasaponins abundant in soybean have anti-inflammatory activities, low-dose SSs alleviated contact hypersensitivity (CHS) symptoms by attenuating inflammation and improving the intestinal microbiota composition, suggesting that dietary SSs may have beneficial effects on allergic contact dermatitis (ACD). 4. Dietary soyasaponin has inhibitory effects on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice.
BCN6390	cis-1-o-Caffeoylquinic acid
1. Soyasaponins has chemoprevention activities, it prevent H₂O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells. 2. Soyasaponins can significantly decrease blood glucose, improve atherosclerotic index, and inhibit lipid peroxidation and platelet aggregation in diabetic rats, which may be useful in prevention and control of diabetes mellitus and diabetes-associated atherosclerosis. 3. Soyasaponins abundant in soybean have anti-inflammatory activities, low-dose SSs alleviated contact hypersensitivity (CHS) symptoms by attenuating inflammation and improving the intestinal microbiota composition, suggesting that dietary SSs may have beneficial effects on allergic contact dermatitis (ACD). 4. Dietary soyasaponin has inhibitory effects on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice.