Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN2832 Magnolioside
Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CIP 53.154.
BCN2839 Pennogenin
1. Pennogenin steroidal saponins could be utilized to develop anticancer medicines.
BCN2842 Buddlejasaponin IVb
Buddlejasaponin IVb(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy.
BCN2843 Angeloylgomisin H
1. Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines. 2. Angeloylgomisin H may present significant myocardial protective activity.
BCN2845 Picfeltarraenin IB
1. Picfeltarraenin IA and Picfeltarraenin IB are Potential PI3K and EGFR Inhibitors. 2. Picfeltarraenin IA and picfeltarraenin IB show stronger AChE inhibition than the known AChE inhibitor Tacrine.
BCN2849 7-O-Methylaloeresin A
1. 7-O-Methylaloeresin A has moderate inhibitory active on BACE. 2. 7-O-Methylaloeresin A shows significant antioxidant activity. 3. 7-O-Methylaloeresin A exhibits good activity against multiple drug resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mm, respectively.
BCN2851 Quercetin 3-O-beta-D-xylopyranoside
1. Quercetin derivatives can be practically applied for the treatment and prevention of osteoporosis, since they effectively inhibit osteoclast proliferation and stimulate osteoblast proliferation more than conventional therapeutic agents for osteoporosis, and increase trabecular bone area highly without changing hormone level in body and untoward effects on hematopoietic function and immune system.
BCN2853 Carlinoside
1. Carlinoside could be a worthy choice to intervene hyperbilirubinemia due to liver dysfunction. 2. Carlinoside upregulates Nrf2 gene expression, increases its nuclear translocation and stimulates UGT1A1 promoter activity.