Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
Cat.No. | Product Name |
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BCN2854 | Soyasaponin Ba |
1. Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase. 2. Soyasaponins(Aa, Ab, Af, Ba, Bb, and Bb') together with their derivatives may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects. | |
BCN2855 | 4',7-Isoflavandiol |
4',7-Isoflavandiol, an estrogen metabolite, affects the ability of soy nuts to improve cardiovascular risk factors. 4',7-Isoflavandiol is a potential anticancer agent against HeLa, with possible mechanisms involved in ROS generation and mitochondrial membrane alteration; it may advance breast cancer potential via up-regulation of the eukaryotic initiation factor 4GI (eIF4GI). | |
BCN2856 | Pseudolaric Acid C |
1. Pseudolaric Acid C shows weak antifungal activity against Candida albicans. | |
BCN1296 | Methyl gypsogenin 3-O-beta-D-glucuronopyranoside |
Gypsogenin 3-O-beta-D-glucuronopyranoside shows inhibitory activity toward pancreatic lipase with IC50 value of 0.29 mM, and the free carboxylic acid groups in position 28 within its chemical structures are required for enhancement of pancreatic lipase inhibition. | |
BCN2857 | Polygalasaponin XXXI |
1. Intranasal vaccination with onjisaponin F(Polygalasaponin XXXI) can inhibit proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice. 2. Onjisaponin F(Polygalasaponin XXXI) acts non-competitively against cyclic AMP phosphodiesterase, like papaverine. 3. Onjisaponin F(Polygalasaponin XXXI) exhibits a prolongation effect on hexobarbital sleeping time in mice. | |
BCN2858 | Jionoside B1 |
1. Jionoside B1 exhibits the obvious inhibition against aldose reductase. 2. Jionoside B1 shows the hepato-protective activity in the H2O2 induced liver injury experiments. 3. Jionoside B1 has immunosuppressive activity. | |
BCN2859 | Picfeltarraenin X |
1. Picfeltarraenin X shows stronger AChE inhibition than the known AChE inhibitor Tacrine. | |
BCN2864 | Vincetoxicoside B |
Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5. |