Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN2926 | Juncusol |
| 1. Juncusol shows significant activity against MRSA strains. 2. Juncusol can induce caspase-3-mediated cytotoxicity in HT22 cells. 3. Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg. | |
| BCN2927 | Dehydroeffusol |
| 1. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. 2. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity, it is a potential drug candidate for anti-gastric cancer neovascularization and anti-gastric cancer therapy. 3. Dehydroeffusol may antagonize the spasmogenic activity of various agents, and therefore, could be a promising agent in the treatment of spasms. 4. Dehydroeffusol possesses anxiolytic and sedative properties and does not affect the general movement coordination of mice. 5. Dehydroeffusol displays enhanced antimicrobial activities in light, its antimicrobial activities (minimum inhibitory concentrations) against methicillin-resistant and -sensitive Staphylococcus aureus and Candida albicans are increased 16 fold by irradiation with ultraviolet A (UVA). | |
| BCN2928 | Effusol |
| 1. Effusol can induce caspase-3-mediated cytotoxicity in HT22 cells. | |
| BCN2929 | Licoisoflavone A |
| 1. Licoisoflavone A is a potential MRP inhibitor. 2. Licoisoflavone A and licoisoflavone B show inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro. | |
| BCN2930 | Glycyrrhisoflavone |
| Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase. Glycybenzofuran shows significant protein tyrosine phosphatase-1B (PTP1B) inhibitory activity in vitro with the IC50 value of 25.5 microM. Glycyrrhisoflavone has anti-inflammatory effects, it has significant inhibitory effects against NO production on LPS-induced RAW 264.7 cell model. | |
| BCN2931 | Semilicoisoflavone B |
| 1. Semilicoisoflavone B can inhibit sorbitol formation of rat lens incubated with a high concentration of glucose, indicates that it may be effective for preventing osmotic stress in hyperglycemia. | |
| BCN2932 | Mauritianin |
| 1. Mauritianin and (+)-syringaresinol as new topoisomerase I inhibitors. 2. Mauritianin has statistically significant cytoprotective activity similar to that of silymarin, tested at 60 ug/mL. | |
| BCN2933 | Alcesefoliside |
| 1. Alcesefoliside has statistically significant cytoprotective activity similar to that of silymarin, tested at 60 ug/mL. | |
