Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1017 - 1024 of 9359 hot products
| Catalog No. | Product Name |
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| BCC4913 | Idebenone |
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Antioxidant and neuroprotective agent. Protects mitochondrial membranes against lipid peroxidation and blocks glutamate neurotoxicity in vitro and in vivo. Inhibits apoptosis of astrocytes via increased NGF production.
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| BCC4914 | Itraconazole |
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SMO antagonist (IC<sub>50</sub> = 690 nM); acts at different binding site to cyclopamine. Also cytochrome p450 inhibitor (IC<sub>50</sub> = 16-26 nM). Inhibits cell cycle at G<sub>1</sub> phase <em>in vitro</em> and blocks angiogenesis <em>in vivo</em> (IC<sub>50</sub> = 160 nM). Antifungal.
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| BCC4915 | L-Ascorbyl 6-palmitate |
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Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C, it is also used as an antioxidant food additive.
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| BCC4920 | Meptazinol HCl |
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Centrally active opioid analgesic. Partial agonist at the <span class='symbol'>μ</span><sub>1</sub> opioid receptor. Also shown to inhibit acetylcholinesterase.
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| BCC4921 | Miglitol |
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Inhibitor of <span class='symbol'>α</span>-glucosidase; antihyperglycemic. Suppresses postprandial hyperglycemia <em>in vivo</em> and reduces plasma glucose concentration in normal rats and in several animal models of diabetes. Shown to inhibit the loss of pancreatic <span class='symbol'>β</span> cells in type 2 diabetic rats. Also inhibits apoptosis and mitochondrial overproduction of reactive oxygen species in endothelial cells <em>in vitro</em>.
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| BCC4922 | Milnacipran HCl |
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Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC<sub>50</sub> values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to <span class='symbol'>α</span><sub>1</sub>-adrenergic and 5-HT<sub>2A</sub> serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities <em>in vivo</em>.
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| BCC4923 | Mirtazapine |
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Antidepressant agent; potent 5-HT<sub>2</sub>, 5-HT<sub>3</sub> and histamine H<sub>1</sub> receptor antagonist and moderately potent <span class='symbol'>α</span><sub>2</sub>-adrenoceptor antagonist (pK<sub>i</sub> values are 8.05, ~ 8.1, 9.3 and 6.95 respectively). Enhances noradrenalin (NA) release in rat brain via inhibition of <span class='symbol'>α</span><sub>2</sub>-adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pK<sub>i</sub> values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration <em>in vivo</em>.
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| BCC4924 | Mitoxantrone HCl |
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Type II DNA topoisomerase inhibitor. Disrupts DNA synthesis and repair and induces damage by DNA cross-linking. Also inhibits PIM1 kinase (IC<sub>50</sub> = 51 nM). Immunomodulatory, antineoplastic and chemotherapeutic agent. Also USP11 inhibitor (IC<sub>50</sub>= 3.15 <span class='symbol'>μ</span>M). Induces cell death of pancreatic cancer cell lines expressing wild-type <em>BRCA2</em>.
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