Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1177 - 1184 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5370 | AZD1283 |
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High affinity P2Y12 antagonist (Kd = 11 nM). Causes a dose-dependent increase in blood flow and inhibits ADP-induced platelet aggregation in vivo. Antithrombotic.
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| BCC5371 | CZC-25146 |
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Potent LRRK2 inhibitor (IC50 values are 4.76 and 6.87 nM for for wild-type and G2019S mutant forms of LRRK2, respectively). Also inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2. Attenuates mutant LRRK2-induced injury of cultured rodent and human neurons. Cell permeable.
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| BCC5372 | BV6 |
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BV6, a small-molecule Smac mimetic, is an antagonist of IAP proteins.
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| BCC5373 | AM580 |
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An analog of retinoic acid that acts as a selective RAR<span class='symbol'>α</span> agonist (EC<sub>50</sub> values are 0.3, 8.6 and 13 nM for RAR<span class='symbol'>α</span>, RAR<span class='symbol'>β</span> and RAR<span class='symbol'>γ</span> respectively). Significantly induces IL-4, IL-5 and IL-13 and inhibits IL-12 and IFN<span class='symbol'>γ</span> synthesis, and induces cell differentiation with over 7 times the activity of retinoic acid <em>in vitro</em>.
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| BCC5375 | Neuropathiazol |
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Selective inducer of neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs). Selectively suppresses astrocyte differentiation when induced by LIF, BMP2 and FBS compared to retinoic acid. Enhances maturation of NPC derived neurons.
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| BCC5379 | PI-3065 |
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Potent and selective PI 3-kinase p110<span class='symbol'>δ</span> inhibitor (IC<sub>50</sub> = 5 nM; K<sub>i</sub> = 1.5 nM). Exhibits >100-fold selectivity over p100<span class='symbol'>α</span>, p100<span class='symbol'>γ</span> and p100<span class='symbol'>β</span> isoforms (IC<sub>50</sub> values are 600, 910, >10,000 nM, respectively). Attenuates 4TI tumor growth and metastasis <em>in vivo</em>.
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| BCC5380 | GBR 12935 dihydrochloride |
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Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).
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| BCC5382 | XEN445 |
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Selective endothelial lipase (EL) inhibitor (IC50 = 237 nM for human EL). Exhibits >20-fold selectivity for EL over lipoprotein lipase (LPL) and hepatic lipase (HL). Increases high density lipoprotein cholesterol (HDLc) plasma levels in mice. Orally bioavailable.
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