Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC5672 | N-MPPP Hydrochloride |
| High affinity κ agonist with no measured binding at μ or δ sites. | |
| BCC5675 | ICI 174,864 |
| Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations. | |
| BCC5677 | ICI 154,129 |
| Selective δ opioid antagonist. | |
| BCC5678 | Pronethalol hydrochloride |
| β-adrenergic antagonist, clinically effective in the treatment of angina pectoris and some arrhythmias. | |
| BCC5683 | Naltriben mesylate |
| Selective and potent δ-opioid receptor antagonist (Ki values are 0.013, 19 and 152 nM for δ, μ and κ receptors respectively). Displays selectivity for the δ2 subtype in vivo. | |
| BCC5684 | Clocinnamox mesylate |
| Systemically active, irreversible μ-opioid receptor antagonist (apparent Ki values are 0.7, 1.9 and 5.7 nM for mouse μ, δ and κ receptors respectively). | |
| BCC5685 | MRS 2179 tetrasodium salt |
| A competitive antagonist at P2Y1 receptors (KB = 100 nM). Selective over P2X1 (IC50 = 1.15 μM), P2X3 (IC50 = 12.9 μM), P2X2, P2X4, P2Y2, P2Y4 and P2Y6 receptors. Inhibits the upregulation of NTPDase1 by ATPγS. | |
| BCC5686 | Nociceptin |
| Endogenous ligand for the NOP opioid receptor (pKi = 8.6). Has no significant activity at μ, δ or κ opioid receptors (pKi < 6). | |
