EffusolCAS# 73166-28-6 |
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| Cas No. | 73166-28-6 | SDF | Download SDF |
| PubChem ID | 100801 | Appearance | Powder |
| Formula | C17H16O2 | M.Wt | 252.3 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5-ethenyl-1-methyl-9,10-dihydrophenanthrene-2,7-diol | ||
| SMILES | CC1=C(C=CC2=C1CCC3=C2C(=CC(=C3)O)C=C)O | ||
| Standard InChIKey | GEXAPRXWKRZPCK-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C17H16O2/c1-3-11-8-13(18)9-12-4-5-14-10(2)16(19)7-6-15(14)17(11)12/h3,6-9,18-19H,1,4-5H2,2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The stem of Juncus effusus L.
| Description | 1. Effusol can induce caspase-3-mediated cytotoxicity in HT22 cells. |
| Targets | Caspase |
Effusol Dilution Calculator
Effusol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.9635 mL | 19.8177 mL | 39.6354 mL | 79.2707 mL | 99.0884 mL |
| 5 mM | 0.7927 mL | 3.9635 mL | 7.9271 mL | 15.8541 mL | 19.8177 mL |
| 10 mM | 0.3964 mL | 1.9818 mL | 3.9635 mL | 7.9271 mL | 9.9088 mL |
| 50 mM | 0.0793 mL | 0.3964 mL | 0.7927 mL | 1.5854 mL | 1.9818 mL |
| 100 mM | 0.0396 mL | 0.1982 mL | 0.3964 mL | 0.7927 mL | 0.9909 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Chemical constituents isolated from Juncus effusus induce cytotoxicity in HT22 cells.[Pubmed:25794817]
J Nat Med. 2015 Jul;69(3):421-6.
Effususol A (1), a new 9,10-dihydrophenanthrene, has been isolated from the medullae of Juncus effusus along with ten known compounds, Effusol (2), dehydroEffusol (3), juncusol (4), dehydrojuncusol (5), juncuenin B (6), dehydrojuncuenin B (7), juncuenin D (8), luteolin (9), luteolin 5-methyl ether (10), and 4-hydroxy-2,3-dimethyl-2-nonen-4-olide (11). The structure of 1 was elucidated on the basis of spectroscopic data. 2, 4, 6, 7, and 8 have induced caspase-3-mediated cytotoxicity in HT22 cells.
Two new anxiolytic phenanthrenes found in the medullae of Juncus effusus.[Pubmed:25233602]
Nat Prod Commun. 2014 Aug;9(8):1177-8.
Six phenanthrenes, 2-methoxy-7-hydroxy-1-methyl-5-vinyl phenanthrene (1), juncusin (2), dehydroEffusol (3), juncusol (4), Effusol (5), and dehydroeffusal (6), were isolated from the medullae of Juncus effusus L. Compounds 1 and 2 were identified as being new structures, and both of them showed anxiolytic activity at dosages of 10 and 2.5 mg/kg, respectively.
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