MauritianinCAS# 109008-28-8 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 109008-28-8 | SDF | Download SDF |
| PubChem ID | 5748188 | Appearance | Yellow powder |
| Formula | C33H40O19 | M.Wt | 740.7 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5,7-dihydroxy-3-[(2R,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy]oxan-2-yl]oxy-2-(4-hydroxyphenyl)chromen-4-one | ||
| SMILES | CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)C)O)O)O)OC4=C(OC5=CC(=CC(=C5C4=O)O)O)C6=CC=C(C=C6)O)CO)O)O)O)O | ||
| Standard InChIKey | AEOBNVBHRFQADS-DNDPRTLXSA-N | ||
| Standard InChI | InChI=1S/C33H40O19/c1-10-19(38)23(42)25(44)31(46-10)50-28-21(40)17(9-34)49-33(30(28)52-32-26(45)24(43)20(39)11(2)47-32)51-29-22(41)18-15(37)7-14(36)8-16(18)48-27(29)12-3-5-13(35)6-4-12/h3-8,10-11,17,19-21,23-26,28,30-40,42-45H,9H2,1-2H3/t10-,11-,17+,19-,20-,21-,23+,24+,25+,26+,28-,30+,31-,32-,33+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Mauritianin and (+)-syringaresinol as new topoisomerase I inhibitors. 2. Mauritianin has statistically significant cytoprotective activity similar to that of silymarin, tested at 60 ug/mL. |
| Targets | Topoisomerase |
Mauritianin Dilution Calculator
Mauritianin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.3501 mL | 6.7504 mL | 13.5007 mL | 27.0015 mL | 33.7519 mL |
| 5 mM | 0.27 mL | 1.3501 mL | 2.7001 mL | 5.4003 mL | 6.7504 mL |
| 10 mM | 0.135 mL | 0.675 mL | 1.3501 mL | 2.7001 mL | 3.3752 mL |
| 50 mM | 0.027 mL | 0.135 mL | 0.27 mL | 0.54 mL | 0.675 mL |
| 100 mM | 0.0135 mL | 0.0675 mL | 0.135 mL | 0.27 mL | 0.3375 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Flavoalkaloids and Flavonoids from Astragalus monspessulanus.[Pubmed:26558405]
J Nat Prod. 2015 Nov 25;78(11):2565-71.
A new flavonol tetraglycoside, quercetin-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->6)]- beta-D-galactopyranosyl]-7-O-beta-D-glucopyranoside (1), and two new flavonol alkaloids, N-(8-methylquercetin-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosy l-(1-->6)]-beta-D-galactopyranosyl])-3-hydroxypiperidin-2-one (2) and N-(8-methylkaempferol-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranos yl-(1-->6)]-beta-D-galactopyranosyl])-3-hydroxypiperidin-2-one (3), were isolated from the aerial parts of Astragalus monspessulanus ssp. monspessulanus. Two rare flavonoids with an unusual 3-hydroxy-3-methylglutaric acid moiety, quercetin-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[6-O-(3-hydroxy-3-methylglutaryl)-b eta-D-galactopyranoside (4) and kaempferol-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[6-O-(3-hydroxy-3-methylglutaryl)- beta-D-galactopyranoside (5), were isolated from the aerial parts of A. monspessulanus ssp. illyricus. In addition, the eight known flavonoids alangiflavoside (6), alcesefoliside (7), Mauritianin (8), quercetin-3-beta-robinobioside (9), cosmosine (10), apigenin-4'-O-glucoside (11), trifolin (12), and rutin (13) were isolated from aerial parts of A. monspessulanus ssp. monspessulanus. Their structures were elucidated via NMR and HRESIMS data. In a model that tested t-BuOOH-induced oxidative stress on isolated rat hepatocytes, flavonoids 1-13 had statistically significant cytoprotective activity similar to that of silymarin, tested at 60 mug/mL. The most prominent effects were observed for flavonoids 1, 4, 7, and 12.
DNA topoisomerase I inhibitors from Rinorea anguifera.[Pubmed:15664863]
Bioorg Med Chem Lett. 2005 Feb 1;15(3):813-6.
An organic extract prepared from Rinorea anguifera was investigated in order to identify the natural principle(s) responsible for stabilization of a topoisomerase I-DNA covalent binary complex. Bioassay-guided fractionation resulted in the isolation of Mauritianin and (+)-syringaresinol as new topoisomerase I inhibitors, and also of the known inhibitor camptothecin.
