Tachioside

CAS# 109194-60-7

Tachioside

Catalog No. BCN5884----Order now to get a substantial discount!

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Tachioside: 5mg $615 In Stock
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Quality Control of Tachioside

Number of papers citing our products

Chemical structure

Tachioside

3D structure

Chemical Properties of Tachioside

Cas No. 109194-60-7 SDF Download SDF
PubChem ID 11962143 Appearance Powder
Formula C13H18O8 M.Wt 302.3
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R,4S,5S,6R)-2-(4-hydroxy-3-methoxyphenoxy)-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES COC1=C(C=CC(=C1)OC2C(C(C(C(O2)CO)O)O)O)O
Standard InChIKey KWVHACHAQJFTLZ-UJPOAAIJSA-N
Standard InChI InChI=1S/C13H18O8/c1-19-8-4-6(2-3-7(8)15)20-13-12(18)11(17)10(16)9(5-14)21-13/h2-4,9-18H,5H2,1H3/t9-,10-,11+,12-,13-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Tachioside

The barks of Pinus yunnanensis

Biological Activity of Tachioside

Description1. Tachioside has antioxidant and α-glucosidase inhibitory activities. 2. Tachioside decreases lipid content in 3T3-L1 adipocytes by inhibiting lipogenesis, shows antiobesity activities. 3. Tachioside can inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 μM.
TargetsNO

Tachioside Dilution Calculator

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Tachioside Molarity Calculator

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Preparing Stock Solutions of Tachioside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.308 mL 16.5399 mL 33.0797 mL 66.1594 mL 82.6993 mL
5 mM 0.6616 mL 3.308 mL 6.6159 mL 13.2319 mL 16.5399 mL
10 mM 0.3308 mL 1.654 mL 3.308 mL 6.6159 mL 8.2699 mL
50 mM 0.0662 mL 0.3308 mL 0.6616 mL 1.3232 mL 1.654 mL
100 mM 0.0331 mL 0.1654 mL 0.3308 mL 0.6616 mL 0.827 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Tachioside

Phenolic glycosides from Glycosmis pentaphylla.[Pubmed:25367455]

J Asian Nat Prod Res. 2014 Dec;16(12):1119-25.

Three new phenolic glycosides, named as glycopentosides A-C (1-3), along with nine known compounds were isolated from the n-BuOH extract of stems of Glycosmis pentaphylla. Their structures were determined by using spectroscopic and chemical methods. Bioassay showed that compound 10 (Tachioside) could inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 muM.

A new phenylpropanoid and an alkylglycoside from Piper retrofractum leaves with their antioxidant and alpha-glucosidase inhibitory activity.[Pubmed:25127165]

Bioorg Med Chem Lett. 2014 Sep 1;24(17):4120-4.

Two new compounds, piperoside (1) and isoheptanol 2(S)-O-beta-D-xylopyranosyl (1-->6)-O-beta-D-glucopyranoside (11), along with 10 known compounds 3,4-dihydroxyallylbenzene (2), 1,2-di-O-beta-D-glucopyranosyl-4-allylbenzene (3), Tachioside (4), benzyl-O-beta-D-glucopyranoside (5), icariside F2 (6), dihydrovomifoliol-3'-O-beta-D-glucopyranoside (7), isopropyl O-beta-D-glucopyranoside (8), isopropyl primeveroside (9), n-butyl O-beta-D-glucopyranoside (10), isoheptanol 2(S)-O-beta-D-apiofuranosyl-(1-->6)-O-beta-D-glucopyranoside (12), were isolated from the leaves of Piper retrofractum. Their structures were determined from 1D-NMR, 2D-NMR, and HR-ESI-MS spectral, a modified Mosher's method, and comparisons with previous reports. All of the isolated compounds showed modest alpha-glucosidase inhibitory (4.60+/-1.74% to 11.97+/-3.30%) and antioxidant activities under the tested conditions.

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