mAChR-IN-1CAS# 119391-56-9 |
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Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 119391-56-9 | SDF | Download SDF |
| PubChem ID | 14479846 | Appearance | Powder |
| Formula | C23H25IN2O2 | M.Wt | 488.36 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : ≥ 52 mg/mL (106.48 mM) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | 3-[1-[(4-iodophenyl)methyl]piperidin-4-yl]-3-phenylpiperidine-2,6-dione | ||
| SMILES | C1CN(CCC1C2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=C(C=C4)I | ||
| Standard InChIKey | WJLRTFJPHDSXAF-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C23H25IN2O2/c24-20-8-6-17(7-9-20)16-26-14-11-19(12-15-26)23(18-4-2-1-3-5-18)13-10-21(27)25-22(23)28/h1-9,19H,10-16H2,(H,25,27,28) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
mAChR-IN-1 Dilution Calculator
mAChR-IN-1 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0477 mL | 10.2383 mL | 20.4767 mL | 40.9534 mL | 51.1917 mL |
| 5 mM | 0.4095 mL | 2.0477 mL | 4.0953 mL | 8.1907 mL | 10.2383 mL |
| 10 mM | 0.2048 mL | 1.0238 mL | 2.0477 mL | 4.0953 mL | 5.1192 mL |
| 50 mM | 0.041 mL | 0.2048 mL | 0.4095 mL | 0.8191 mL | 1.0238 mL |
| 100 mM | 0.0205 mL | 0.1024 mL | 0.2048 mL | 0.4095 mL | 0.5119 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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mAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17 nM.
References:
[1]. Wilson AA, et al. Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist. J Med Chem. 1989 May;32(5):1057-62.
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mAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17 nM.
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