BCN4763CassyfilineBotanical source: The herbs of Cassytha filiformis(CAS NO.:4030-51-7)
BCN3896Cannabisin HBotanical source: The herbs of Cannabis sativa L.(CAS NO.:403647-08-5)
BCN1016CapsaicinCapsaicin ((E)-Capsaicin) is a mixture of Capsaicin and Dihydrocapsaicin. Capsaici is a TRPV1 agonist with an EC50 of 0.29 μM in HEK293 cells.(CAS NO.:404-86-4)
BCN1744ActinineBotanical source: The herbs of Polyporus sulphureus(CAS NO.:407-64-7)
BCN5461Sinoacutine(-)-Salutaridine (Salutaridine) is an alkaloid isolated from the stems of Sinomenium acutum.(CAS NO.:4090-18-0)
BCN5332Stachydrine hydrochlorideStachydrine hydrochloride is the major active constituent of Herba Leonuri, which is a potential therapy for cardiovascular diseases. Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities.(CAS NO.:4136-37-2)
BCN5469(-)-N-MethylsedridineBotanical source: The herbs of Sedum sarmentosum(CAS NO.:41447-15-8)
BCN5470(+)-N-MethylallosedridineBotanical source: The herbs of Sedum sarmentosum(CAS NO.:41447-16-9)
BCN2911Magnoflorine Iodide(+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm. (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity.(CAS NO.:4277-43-4)
BCN2609VinpocetineVinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders.(CAS NO.:42971-09-5)
BCN2673(-)-Curine(-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated from Chondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition of prostaglandin E2 production.(CAS NO.:436-05-5)
BCN5956FangchinolineFangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing. Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK. Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer.(CAS NO.:436-77-1)
BCN3867AjmalineAjmaline is an alkaloid that is class Ia antiarrhythmic agent.(CAS NO.:4360-12-7)
BCN1035TetrodotoxinTetrodotoxin is a highly selective sodium channel blocker, with IC50 of 33 nM for Nav1.6.(CAS NO.:4368-28-9)
BCN5491PerakinePerakine is an indole alkaloid isolated from Alstonia yunnanensis. Anti-inflammatory activities.(CAS NO.:4382-56-3)
BCN5494HarmineHarmine is a natural dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT2A serotonin receptor, with an Ki of 397 nM.(CAS NO.:442-51-3)
