BCN5532LiriodenineBotanical source: The barks of Liriodendron chinense (Hemsl.) Sarg.(CAS NO.:475-75-2)
BCN2550GlaucineBotanical source: The tubers of Corydalis yanhusuo(CAS NO.:475-81-0)
BCN1223NuciferineNuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.(CAS NO.:475-83-2)
BCN2409LycorineLycorine is a natural alkaloid extracted from the Amaryllidaceae plant family with antiviral, antimalarial and antiinflammation activities. Lycorine inhibits the growth and metastasis of hormone-refractory anti-prostate cancer (PCa) and induces cell apoptosis.(CAS NO.:476-28-8)
BCN2463ChelidonineBotanical source: The herbs of Chelidonium majus L.(CAS NO.:476-32-4)
BCN2669CorydineCorydine is a naturally occurring alkaloid which can be extracted from plants such as Croton echinocarpus leaves. Corydine is efficient on inhibiting reverse transcriptase (RT) activity with an IC50 of 356.8 μg/mL. Corydine displays significant in vitro anti-HIV potential, inhibiting 40% of the HIV-1 reverse transcriptase enzyme activity at a concentration of 450 μg/mL of Corydine.(CAS NO.:476-69-7)
BCN5534BoldineBoldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis.(CAS NO.:476-70-0)
BCN2507LycorenineBotanical source: The rhizomes of Lycoris radiata(CAS NO.:477-19-0)
BCN5538IsotetrandrineBotanical source: The roots of Stephania tetrandra S.Moore(CAS NO.:477-57-6)
BCN5541NeostenineBotanical source: The roots of Stemona sessilifolia(CAS NO.:477953-07-4)
BCN5543BerbamineBerbamine is a natural compound extracted from traditional Chinese medicine Barberry with anti-tumor, immunomodulatory and cardiovascular effects. Berbamine is a calcium channel blocker.(CAS NO.:478-61-5)
BCN5563SeneciphyllineSeneciphylline is a toxic pyrrolizidine alkaloid in Senecio plants. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities.(CAS NO.:480-81-9)
