BCN651010-HydroxyneolineBotanical source: The roots of Aconitum fukutomei(CAS NO.:132362-42-6)
BCN2130Senecionine N-oxideSenecionine n-oxide is the primary product of pyrrolizidine alkaloid biosynthesis in root cultures of Senecio vulgaris. Senecionine N-oxide has anti-cancer activity.(CAS NO.:13268-67-2)
BCN1793Crassifoline methineBotanical source: The herbs of Corydalis claviculata(CAS NO.:133084-00-1)
BCN1843LydicamycinBotanical source: The Streptomyces aureofaciens(CAS NO.:133352-27-9)
BCN2456Aristololactam IAristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway.(CAS NO.:13395-02-3)
BCN1932PseudotropineBotanical source: The roots of Atropa belladonna(CAS NO.:135-97-7)
BCN2374Bullatine ABullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A is a potent P2X7 antagonist, inhibits ATP-induced cell death/apoptosis and P2X receptor-mediated inflammatory responses. Bullatine A attenuates pain hypersensitivity, regardless of the pain models employed.(CAS NO.:1354-84-3)
BCN2171Palonosetron hydrochloridePalonosetron Hcl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).(CAS NO.:135729-62-3)
BCN6190KoumineKoumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells. Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities, protects against the development of arthritis in Rheumatoid arthritis (RA) animal models.(CAS NO.:1358-76-5)
BCN7499Caulophylline BCaulophylline B is a fluorenone alkaloid isolated from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical.(CAS NO.:1359978-55-4)
BCN3870RanaconitineRanaconitine is a diterpene alkaloid isolated from A. leucostomum, with cardiotoxicity.(CAS NO.:1360-76-5)
BCN811914-DehydrodelcosineBotanical source: The herbs of Delphinium davidii(CAS NO.:1361-18-8)