1-Acetyl-beta-carbolineCAS# 50892-83-6 |
Quality Control & MSDS
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| Cas No. | 50892-83-6 | SDF | Download SDF |
| PubChem ID | 638667 | Appearance | Cryst |
| Formula | C13H10N2O | M.Wt | 210.2 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-(9H-pyrido[3,4-b]indol-1-yl)ethanone | ||
| SMILES | CC(=O)C1=NC=CC2=C1NC3=CC=CC=C23 | ||
| Standard InChIKey | NXZSUJKPVSDFNF-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The barks of Picrasma quassioides
| Description | 1. Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA. |
| Targets | Antifection |
1-Acetyl-beta-carboline Dilution Calculator
1-Acetyl-beta-carboline Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.7574 mL | 23.7869 mL | 47.5737 mL | 95.1475 mL | 118.9343 mL |
| 5 mM | 0.9515 mL | 4.7574 mL | 9.5147 mL | 19.0295 mL | 23.7869 mL |
| 10 mM | 0.4757 mL | 2.3787 mL | 4.7574 mL | 9.5147 mL | 11.8934 mL |
| 50 mM | 0.0951 mL | 0.4757 mL | 0.9515 mL | 1.9029 mL | 2.3787 mL |
| 100 mM | 0.0476 mL | 0.2379 mL | 0.4757 mL | 0.9515 mL | 1.1893 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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The synergistic antibacterial activity of 1-acetyl-beta-carboline and beta-lactams against methicillin-resistant Staphylococcus aureus (MRSA).[Pubmed:20372018]
J Microbiol Biotechnol. 2010 Mar;20(3):501-5.
1-Acetyl-beta-carboline was isolated as an anti-MRSA agent from the fermentation broth of a marine actinomycete isolated from marine sediment. The producing strain was identified to be Streptomyces sp. by phylogenetic analysis of the 16S rRNA gene sequence. The anti-MRSA agent was isolated by bioactivity-guided fractionation of the culture extract by solvent partitioning, ODS open flash chromatography, and purification with a reversed-phase HPLC. Its structure was elucidated by extensive 2D NMR and mass spectral analyses. Combination of 1-acetyl-beta- carboline with ampicillin exhibited synergistic antibacterial activity against MRSA.
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