Neoliquiritin

CAS# 5088-75-5

Neoliquiritin

Catalog No. BCN6663----Order now to get a substantial discount!

Product Name & Size Price Stock
Neoliquiritin: 5mg Please Inquire In Stock
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Quality Control of Neoliquiritin

Number of papers citing our products

Chemical structure

Neoliquiritin

3D structure

Chemical Properties of Neoliquiritin

Cas No. 5088-75-5 SDF Download SDF
PubChem ID 51666248 Appearance Powder
Formula C21H22O9 M.Wt 418.4
Type of Compound Flavonoids Storage Desiccate at -20°C
Synonyms 4',7-Dihydroxyflavanone 7-glucoside; Liquiritigenin 7-glucoside
Solubility Soluble in methan
Chemical Name (2S)-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one
SMILES C1C(OC2=C(C1=O)C=CC(=C2)OC3C(C(C(C(O3)CO)O)O)O)C4=CC=C(C=C4)O
Standard InChIKey HJBUYKZTEBZNSH-ZRWXNEIDSA-N
Standard InChI InChI=1S/C21H22O9/c22-9-17-18(25)19(26)20(27)21(30-17)28-12-5-6-13-14(24)8-15(29-16(13)7-12)10-1-3-11(23)4-2-10/h1-7,15,17-23,25-27H,8-9H2/t15-,17+,18+,19-,20+,21+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Neoliquiritin

The roots of Glycyrrhiza uralensis.

Biological Activity of Neoliquiritin

DescriptionStandard reference
In vitro

Assessment of genetic fidelity and composition: Mixed elicitors enhance triterpenoid and flavonoid biosynthesis of Glycyrrhiza uralensis Fisch. tissue cultures.[Pubmed: 26872048 ]

Biotechnol Appl Biochem. 2017 Mar;64(2):211-217.

Glycyrrhiza uralensis has acquired significant importance due to its medicinal properties and health function. In this study, the quality of G. uralensis adventitious roots was evaluated in terms of genetic stability, active compounds, and anti-inflammatory activity.
METHODS AND RESULTS:
Monomorphic banding pattern obtained from the mother plant and tissue cultures of G. uralensis with randomly amplified polymorphic DNA markers confirmed the genetic stability of adventitious roots. Neoliquiritin (neoisoliquiritin), ononin, liquiritin, and glycyrrhizic acid were identified from G. uralensis adventitious roots on the basis of high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry analysis. This study also revealed that adventitious roots possessed a better anti-inflammatory effect than native roots. To increase the contents of G. uralensis active components, elicitors were used in the adventitious roots culture. The combination of methyl jasmonate and phenylalanine synergistically stimulated the accumulation of glycyrrhetinic acid (0.22 mg/g) and total flavonoid (5.43 mg/g) compared with single treatment.
CONCLUSIONS:
In conclusion, G. uralensis adventitious roots can be an exploitable system for the production of licorice.

Neoliquiritin Dilution Calculator

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Neoliquiritin Molarity Calculator

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Preparing Stock Solutions of Neoliquiritin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3901 mL 11.9503 mL 23.9006 mL 47.8011 mL 59.7514 mL
5 mM 0.478 mL 2.3901 mL 4.7801 mL 9.5602 mL 11.9503 mL
10 mM 0.239 mL 1.195 mL 2.3901 mL 4.7801 mL 5.9751 mL
50 mM 0.0478 mL 0.239 mL 0.478 mL 0.956 mL 1.195 mL
100 mM 0.0239 mL 0.1195 mL 0.239 mL 0.478 mL 0.5975 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Neoliquiritin

Assessment of genetic fidelity and composition: Mixed elicitors enhance triterpenoid and flavonoid biosynthesis of Glycyrrhiza uralensis Fisch. tissue cultures.[Pubmed:26872048]

Biotechnol Appl Biochem. 2017 Mar;64(2):211-217.

Glycyrrhiza uralensis has acquired significant importance due to its medicinal properties and health function. In this study, the quality of G. uralensis adventitious roots was evaluated in terms of genetic stability, active compounds, and anti-inflammatory activity. Monomorphic banding pattern obtained from the mother plant and tissue cultures of G. uralensis with randomly amplified polymorphic DNA markers confirmed the genetic stability of adventitious roots. Neoliquiritin (neoisoliquiritin), ononin, liquiritin, and glycyrrhizic acid were identified from G. uralensis adventitious roots on the basis of high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry analysis. This study also revealed that adventitious roots possessed a better anti-inflammatory effect than native roots. To increase the contents of G. uralensis active components, elicitors were used in the adventitious roots culture. The combination of methyl jasmonate and phenylalanine synergistically stimulated the accumulation of glycyrrhetinic acid (0.22 mg/g) and total flavonoid (5.43 mg/g) compared with single treatment. In conclusion, G. uralensis adventitious roots can be an exploitable system for the production of licorice.

Description

Neoliquiritin is isolated from Glycyrrhiza uralensis with an anti-inflammatory activity.

Keywords:

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