1-Hydroxy-2-methylanthraquinoneCAS# 6268-09-3 |
Quality Control & MSDS
3D structure
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| Cas No. | 6268-09-3 | SDF | Download SDF |
| PubChem ID | 160817 | Appearance | Yellow cryst. |
| Formula | C15H10O3 | M.Wt | 238.2 |
| Type of Compound | Anthraquinones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-hydroxy-2-methylanthracene-9,10-dione | ||
| SMILES | CC1=C(C2=C(C=C1)C(=O)C3=CC=CC=C3C2=O)O | ||
| Standard InChIKey | CZODYZFOLUNSFR-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. 1-Hydroxy-2-methylanthraquinone exhibits promising larvicidal activity. |
1-Hydroxy-2-methylanthraquinone Dilution Calculator
1-Hydroxy-2-methylanthraquinone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.1982 mL | 20.9908 mL | 41.9815 mL | 83.9631 mL | 104.9538 mL |
| 5 mM | 0.8396 mL | 4.1982 mL | 8.3963 mL | 16.7926 mL | 20.9908 mL |
| 10 mM | 0.4198 mL | 2.0991 mL | 4.1982 mL | 8.3963 mL | 10.4954 mL |
| 50 mM | 0.084 mL | 0.4198 mL | 0.8396 mL | 1.6793 mL | 2.0991 mL |
| 100 mM | 0.042 mL | 0.2099 mL | 0.4198 mL | 0.8396 mL | 1.0495 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A new anthraquinone from Morinda citrifolia roots.[Pubmed:19735047]
Nat Prod Res. 2009;23(14):1322-9.
An investigation of Morinda citrifolia roots afforded a new anthraquinone, 2-ethoxy-1-hydroxyanthraquinone (1), along with five other known anthraquinones: 1-Hydroxy-2-methylanthraquinone (2), damnacanthal (3), nordamnacanthal (4), 2-formyl-1-hydroxyanthraquinone (5) and morindone-6-methyl-ether (6). This is the first report on the isolation of morindone-6-methyl-ether (6) from this plant. The structures of these compounds were elucidated based on spectroscopic analyses such as NMR, MS and IR. Biological evaluation of five pure compounds and all the extracts against the larvae of Aedes aegypti indicated 1-Hydroxy-2-methylanthraquinone (2) and damnacanthal (3) were the extracts to exhibit promising larvicidal activities.
Isolation, structure elucidation, and cytotoxic evaluation of furanonaphthoquinones from in vitro plantlets and cultures of Streptocarpus dunnii.[Pubmed:21174407]
J Nat Prod. 2011 Jan 28;74(1):82-5.
Two new furanonaphthoquinones, (3R)-7-methoxy-alpha-dunnione (5) and (3R)-6-hydroxy-7-methoxy-alpha-dunnione (6), along with the known (3R)-dunnione (1), (3R)-alpha-dunnione (2), (3R)-7-hydroxy-alpha-dunnione (3), and 1-Hydroxy-2-methylanthraquinone (4), were isolated from in vitro cultures of Streptocarpus dunnii. The structures of compounds 5 and 6 were established by spectroscopic means. This is the first report of hydroxylated furanonaphthoquinones in a Streptocarpus species. Compounds 1-3 demonstrated cytotoxic activity against a range of breast cancer and pancreatic tumor cell lines.
Two new hydronaphthoquinones from Sinningia aggregata (Gesneriaceae) and cytotoxic activity of aggregatin D.[Pubmed:25641842]
Chem Biodivers. 2015 Jan;12(1):148-52.
Two new hydronaphthoquinones, aggregatins E and F (1 and 2, resp.) were isolated from the tubers of Sinningia aggregata (Ker-Gawl.) Wiehler (Gesneriaceae), along with twelve known compounds aggregatin D (3), tectoquinone (4), 1-Hydroxy-2-methylanthraquinone (5), icosyl ferulate (6), pustuline (7), 1,6-dihydroxy-2-methylanthranquinone (8), 6-hydroxy-2-methylanthraquinone (9), 7-hydroxy-2-methylanthraquinone (10), tyrosol (11), halleridone (12), calceolarioside B (13), and cornoside (14). All compounds were identified by analysis of spectroscopic and spectrometric data. Compounds 3, 4, and 10 had already been reported in this species. Compounds 2 and 3 were evaluated against several tumor cell lines, but only 3 exhibited activities against UACC-62, 786-0 and OVCAR-3 cell lines, with IC50 values of 12.3, 12.8 and 0.3 mug/ml, respectively, without toxic effects on non-cancer cell line HaCat (human keratinocyte).
