11-HydroxycodaphniphyllineCAS# 1186496-68-3 |
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| Cas No. | 1186496-68-3 | SDF | Download SDF |
| PubChem ID | 131845296 | Appearance | Powder |
| Formula | C30H47NO4 | M.Wt | 485.7 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC(C)C1CCC2(C3CC(C45CCCC4C2(C1N5C3)CCC(=O)C6(COC7(CCC6O7)C)C)O)C | ||
| Standard InChIKey | JENRSDUHJGGCGW-UNMUNERDSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The leaves of Daphniphyllum subverticillatum
| Description | Standard reference |
| In vitro | Alkaloids from the leaves of Daphniphyllum subverticillatum.[Pubmed: 19739650]J Nat Prod. 2009 Sep;72(9):1669-72.
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11-Hydroxycodaphniphylline Dilution Calculator
11-Hydroxycodaphniphylline Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0589 mL | 10.2944 mL | 20.5888 mL | 41.1777 mL | 51.4721 mL |
| 5 mM | 0.4118 mL | 2.0589 mL | 4.1178 mL | 8.2355 mL | 10.2944 mL |
| 10 mM | 0.2059 mL | 1.0294 mL | 2.0589 mL | 4.1178 mL | 5.1472 mL |
| 50 mM | 0.0412 mL | 0.2059 mL | 0.4118 mL | 0.8236 mL | 1.0294 mL |
| 100 mM | 0.0206 mL | 0.1029 mL | 0.2059 mL | 0.4118 mL | 0.5147 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Alkaloids from the leaves of Daphniphyllum subverticillatum.[Pubmed:19739650]
J Nat Prod. 2009 Sep;72(9):1669-72.
Four new alkaloids, 17-hydroxydaphnigraciline (1), subdaphnidine A (2), daphnezomine L methyl ester (3), and 11-Hydroxycodaphniphylline (4), along with 24 known analogues, were isolated from the leaves of Daphniphyllum subverticillatum. The structures of 1-4 were elucidated on the basis of spectroscopic methods and from chemical evidence. Daphnilongeridine (5) showed cytotoxicity against several tumor cell lines at IC(50) values in the range 2.4-9.7 microM and against the HMEC human microvascular endothelial cell line with an IC(50) of 2.7 microM.
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