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11-Hydroxycodaphniphylline

CAS# 1186496-68-3

11-Hydroxycodaphniphylline

Catalog No. BCN6061----Order now to get a substantial discount!

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11-Hydroxycodaphniphylline: 5mg Please Inquire In Stock
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11-Hydroxycodaphniphylline: 1000mg Please Inquire Please Inquire

Quality Control of 11-Hydroxycodaphniphylline

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Chemical structure

11-Hydroxycodaphniphylline

3D structure

Chemical Properties of 11-Hydroxycodaphniphylline

Cas No. 1186496-68-3 SDF Download SDF
PubChem ID 131845296 Appearance Powder
Formula C30H47NO4 M.Wt 485.7
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(C)C1CCC2(C3CC(C45CCCC4C2(C1N5C3)CCC(=O)C6(COC7(CCC6O7)C)C)O)C
Standard InChIKey JENRSDUHJGGCGW-UNMUNERDSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 11-Hydroxycodaphniphylline

The leaves of Daphniphyllum subverticillatum

Biological Activity of 11-Hydroxycodaphniphylline

DescriptionStandard reference
In vitro

Alkaloids from the leaves of Daphniphyllum subverticillatum.[Pubmed: 19739650]

J Nat Prod. 2009 Sep;72(9):1669-72.


METHODS AND RESULTS:
Four new alkaloids, 17-hydroxydaphnigraciline (1), subdaphnidine A (2), daphnezomine L methyl ester (3), and 11-Hydroxycodaphniphylline (4), along with 24 known analogues, were isolated from the leaves of Daphniphyllum subverticillatum. The structures of 1-4 were elucidated on the basis of spectroscopic methods and from chemical evidence.
CONCLUSIONS:
Daphnilongeridine (5) showed cytotoxicity against several tumor cell lines at IC(50) values in the range 2.4-9.7 microM and against the HMEC human microvascular endothelial cell line with an IC(50) of 2.7 microM.

11-Hydroxycodaphniphylline Dilution Calculator

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11-Hydroxycodaphniphylline Molarity Calculator

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Preparing Stock Solutions of 11-Hydroxycodaphniphylline

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0589 mL 10.2944 mL 20.5888 mL 41.1777 mL 51.4721 mL
5 mM 0.4118 mL 2.0589 mL 4.1178 mL 8.2355 mL 10.2944 mL
10 mM 0.2059 mL 1.0294 mL 2.0589 mL 4.1178 mL 5.1472 mL
50 mM 0.0412 mL 0.2059 mL 0.4118 mL 0.8236 mL 1.0294 mL
100 mM 0.0206 mL 0.1029 mL 0.2059 mL 0.4118 mL 0.5147 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 11-Hydroxycodaphniphylline

Alkaloids from the leaves of Daphniphyllum subverticillatum.[Pubmed:19739650]

J Nat Prod. 2009 Sep;72(9):1669-72.

Four new alkaloids, 17-hydroxydaphnigraciline (1), subdaphnidine A (2), daphnezomine L methyl ester (3), and 11-Hydroxycodaphniphylline (4), along with 24 known analogues, were isolated from the leaves of Daphniphyllum subverticillatum. The structures of 1-4 were elucidated on the basis of spectroscopic methods and from chemical evidence. Daphnilongeridine (5) showed cytotoxicity against several tumor cell lines at IC(50) values in the range 2.4-9.7 microM and against the HMEC human microvascular endothelial cell line with an IC(50) of 2.7 microM.

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