Cuniloside B

CAS# 1187303-40-7

Cuniloside B

Catalog No. BCN6062----Order now to get a substantial discount!

Product Name & Size Price Stock
Cuniloside B: 5mg $886 In Stock
Cuniloside B: 10mg Please Inquire In Stock
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Quality Control of Cuniloside B

Number of papers citing our products

Chemical structure

Cuniloside B

3D structure

Chemical Properties of Cuniloside B

Cas No. 1187303-40-7 SDF Download SDF
PubChem ID 91895372 Appearance Powder
Formula C26H40O10 M.Wt 512.6
Type of Compound Monoterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(4R)-4-(2-hydroxypropan-2-yl)cyclohexene-1-carbonyl]oxyoxan-2-yl]methyl (4R)-4-(2-hydroxypropan-2-yl)cyclohexene-1-carboxylate
SMILES CC(C)(C1CCC(=CC1)C(=O)OCC2C(C(C(C(O2)OC(=O)C3=CCC(CC3)C(C)(C)O)O)O)O)O
Standard InChIKey JOLLIDAUJSAZHE-SKNUFNKISA-N
Standard InChI InChI=1S/C26H40O10/c1-25(2,32)16-9-5-14(6-10-16)22(30)34-13-18-19(27)20(28)21(29)24(35-18)36-23(31)15-7-11-17(12-8-15)26(3,4)33/h5,7,16-21,24,27-29,32-33H,6,8-13H2,1-4H3/t16-,17-,18+,19+,20-,21+,24-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cuniloside B

The herbs of Eucalyptus microcory

Biological Activity of Cuniloside B

Description1. Cuniloside B shows anti-leishmanial activity.
TargetsAntifection

Cuniloside B Dilution Calculator

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Cuniloside B Molarity Calculator

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Preparing Stock Solutions of Cuniloside B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9508 mL 9.7542 mL 19.5084 mL 39.0168 mL 48.771 mL
5 mM 0.3902 mL 1.9508 mL 3.9017 mL 7.8034 mL 9.7542 mL
10 mM 0.1951 mL 0.9754 mL 1.9508 mL 3.9017 mL 4.8771 mL
50 mM 0.039 mL 0.1951 mL 0.3902 mL 0.7803 mL 0.9754 mL
100 mM 0.0195 mL 0.0975 mL 0.1951 mL 0.3902 mL 0.4877 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Cuniloside B

Terpenoidal constituents of Eucalyptus loxophleba ssp. lissophloia.[Pubmed:22468852]

Pharm Biol. 2012 Jul;50(7):823-7.

CONTEXT: Eucalyptus has been a source of a number of biologically active compounds. The anti-leishmanial activity of terpenoids from Eucalyptus loxophleba (Benth.) ssp. lissophloia (Myrtaceae) has not yet been investigated. OBJECTIVE: Isolation of the terpenoidal constituents for evaluation of in vitro anti-leishmanial activity against the Leishmania donovani (Dd8 strain) promastigotes. MATERIALS AND METHODS: The chloroform-methanol (8:2) extract of dried leaves of Eucalyptus loxophleba was used to isolate terpenoidal constituents employing solvent partitioning, column chromatography and preparative high performance liquid chromatography and characterized from spectral data. The anti-leishmanial activity of the isolated compounds was tested in vitro using an Alamar blue assay against a culture of L. donovani (Dd8 strain) promastigotes. RESULTS: Two new naturally occurring triterpenes, named loxanic acid and 3-acetyl loxanic acid together with four known ursane triterpenoids and one bis-monoterpene glycoside, Cuniloside B isolated from the leaves showed anti-leishmanial activity (IC(50) 133 to 235 muM) against the promastigotes of the tested strain. CONCLUSION: The terpenes isolated from the leaves of E. loxophleba showed moderate anti-leishmanial activity.

Synthesis of the monoterpenoid esters cypellocarpin C and cuniloside B and evidence for their widespread occurrence in Eucalyptus.[Pubmed:20708173]

Carbohydr Res. 2010 Sep 23;345(14):2079-84.

Short syntheses of Cuniloside B and cypellocarpin C, (+)-(R)-oleuropeic acid-containing carbohydrates, are reported. Also disclosed are syntheses of the noreugenin glycosides, undulatoside A and corymbosins K(1) and K(2). Leaf extracts of 28 diverse eucalypts revealed Cuniloside B to be present in all, and cypellocarpin C to be present in most, of the species examined. The widespread occurrence of these carbohydrate monoterpenoid esters supports their roles in essential oil biosynthesis or mobilization from sites of synthesis to secretory cavity lumena.

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