Home >> Research Area >>Natural Products>>Monoterpenoids>> 2,2,5,5-Tetramethylcyclohexane-1,4-dione

2,2,5,5-Tetramethylcyclohexane-1,4-dione

CAS# 86838-54-2

2,2,5,5-Tetramethylcyclohexane-1,4-dione

Catalog No. BCN1324----Order now to get a substantial discount!

Product Name & Size Price Stock
2,2,5,5-Tetramethylcyclohexane-1,4-dione: 5mg $265 In Stock
2,2,5,5-Tetramethylcyclohexane-1,4-dione: 10mg Please Inquire In Stock
2,2,5,5-Tetramethylcyclohexane-1,4-dione: 20mg Please Inquire Please Inquire
2,2,5,5-Tetramethylcyclohexane-1,4-dione: 50mg Please Inquire Please Inquire
2,2,5,5-Tetramethylcyclohexane-1,4-dione: 100mg Please Inquire Please Inquire
2,2,5,5-Tetramethylcyclohexane-1,4-dione: 200mg Please Inquire Please Inquire
2,2,5,5-Tetramethylcyclohexane-1,4-dione: 500mg Please Inquire Please Inquire
2,2,5,5-Tetramethylcyclohexane-1,4-dione: 1000mg Please Inquire Please Inquire

Quality Control of 2,2,5,5-Tetramethylcyclohexane-1,4-dione

Number of papers citing our products

Chemical structure

2,2,5,5-Tetramethylcyclohexane-1,4-dione

3D structure

Chemical Properties of 2,2,5,5-Tetramethylcyclohexane-1,4-dione

Cas No. 86838-54-2 SDF Download SDF
PubChem ID 13390715 Appearance Powder
Formula C10H16O2 M.Wt 168.2
Type of Compound Monoterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2,2,5,5-tetramethylcyclohexane-1,4-dione
SMILES CC1(CC(=O)C(CC1=O)(C)C)C
Standard InChIKey OTQZSPVHJYLKOL-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2,2,5,5-Tetramethylcyclohexane-1,4-dione

The herbs of Liriodendron tulipifera

2,2,5,5-Tetramethylcyclohexane-1,4-dione Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

2,2,5,5-Tetramethylcyclohexane-1,4-dione Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 2,2,5,5-Tetramethylcyclohexane-1,4-dione

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.9453 mL 29.7265 mL 59.453 mL 118.9061 mL 148.6326 mL
5 mM 1.1891 mL 5.9453 mL 11.8906 mL 23.7812 mL 29.7265 mL
10 mM 0.5945 mL 2.9727 mL 5.9453 mL 11.8906 mL 14.8633 mL
50 mM 0.1189 mL 0.5945 mL 1.1891 mL 2.3781 mL 2.9727 mL
100 mM 0.0595 mL 0.2973 mL 0.5945 mL 1.1891 mL 1.4863 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 2,2,5,5-Tetramethylcyclohexane-1,4-dione

Synthesis and fluorescence studies of nine 1,5-benzodiazepine-2,4-dione derivatives: Dual emission and excimer fluorescence.[Pubmed:27894000]

Spectrochim Acta A Mol Biomol Spectrosc. 2017 Mar 5;174:164-170.

The photophysical properties of nine 1,5-benzodiazepine-2,4-dione (BZD) derivatives were investigated using absorption and fluorescence spectral techniques in dimethyl sulfoxide. The trend of red shifts caused by the substitutions had full compliance with the trend of decreasing the calculated band gap (DeltaELUMO-HOMO) by semi-empirical AM1 and DFT/B3LYP/6-311+G* computational methods. The positive solvatochromism of BZD a demonstrated the pi-pi* nature of the singlet excited state. Dual fluorescence was observed in the emission spectra of BZD f and g, while their spectrum in different concentration showed only one peak short wavelength (SW) in dilute solutions. The main peak in SW around 370nm was attributed to the monomer of BZD (f* or g*) and the broader emission shifted to the visible region around 400nm in middle wavelength (MW) to the intermolecular excimer emission of BZD ([f/f]*or [g/g]*). The observed phenomena, such as solvatochromism, dual fluorescence, some red shifts caused by substitution, and larger Stokes shift indicated the existence of intramolecular charge transfer (ICT) in the BZDs series. The phosphorescence emission of the BZDs demonstrated their intersystem crossing (ISC) process.

Synthesis, biological evaluation and in silico studies of 5-(3-methoxybenzylidene)thiazolidine-2,4-dione analogues as PTP1B inhibitors.[Pubmed:28126289]

Bioorg Chem. 2017 Apr;71:1-9.

PTP1B (protein tyrosine phosphatase 1B) dephosphorylates the insulin receptor substrate and thus acts as a negative regulator of the insulin and leptin signalling pathway. Recently, it has been considered as a new therapeutic target of intervention for the treatment of type2 diabetes. A series of aryl/alkylsulfonyloxy-5-(3-methoxybenzylidene)thiazolidine-2,4-dione derivatives were synthesized, screened in vitro for their PTP1B inhibitory activity and in vivo for anti-hyperglycaemic activity. Docking results further helped in understanding the nature of interactions governing the binding mode of ligands inside the active site of PTP1B. Among the synthesized compounds, 13 and 16 were found to be potent PTP1B inhibitors having IC50 of 7.31 and 8.73muM respectively. Significant lowering of blood glucose level was observed in some of the synthesized compounds in in vivo study.

Programmable self-assembly of water-soluble organo-heterometallic cages [M12M'4L12] using 3-(3,5-dimethyl-1H-pyrazol-4-yl)pentane-2,4-dione (H2L).[Pubmed:28361135]

Chem Commun (Camb). 2017 Apr 11;53(30):4238-4241.

A bifunctional ligand H2L featuring primary (pyrazole) and secondary (acetylacetone) coordination sites was preferentially reacted with dimetallic [M2(NO3)2](NO3)2 linkers at the pyrazolyl end of H2L, giving rise to dimetallic corners. Subsequently, the corners serve as the secondary site with M' to form water-soluble organo-heterometallic [M12M'4L12] cages in a stepwise mode.

Protective Effects of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Isolated from Averrhoa Carambola L. (Oxalidaceae) Roots on High-Fat Diet-Induced Obesity and Insulin Resistance in Mice.[Pubmed:27941348]

Cell Physiol Biochem. 2016;40(5):993-1004.

BACKGROUND/AIMS: The roots of Averrhoa carambola L. (Oxalidaceae) have long been used as a traditional Chinese medicine for the treatment of diabetes and diabetes-related diseases. 2-dodecyl-6-methoxycycyclohexa-2,5-1,4-dione (DMDD) has been isolated from A. carambola L. roots, and this study was carried out to investigate the potential beneficial effects of DMDD on obesity and insulin resistance induced by a high-fat diet (HFD) in mice. METHODS: C57BL/6J mice were fed a HFD for 16 weeks and orally administered DMDD (12.5, 25, or 50 mg/kg of body weight per day) and metformin (280 mg/kg of body weight per day) for the last 4 weeks. RESULTS: The body weights and adipose tissue weights as well as the serum levels of blood glucose, total cholesterol, triglycerides, free fatty acids, insulin, interleukin-6, and tumor necrosis factor-alpha were significantly decreased by DMDD, and the expression of Toll-like receptor 4 (TLR4) and myeloid differentiation factor (Myd88) in the epididymal adipose tissue was downregulated by DMDD. In contrast, insulin sensitivity was enhanced. The results of the glucose tolerance tests, insulin tolerance tests, and insulin release tests indicated that there was a marked improvement in insulin secretion, and the areas under the curve corresponding to the three tests were also significantly decreased by DMDD. The activities of superoxide dismutase and glutathione peroxidase were simultaneously enhanced, whereas the content of malondialdehyde was decreased by DMDD in the liver homogenates of the C57BL/6J mice. In addition, hepatic steatosis and adipocyte hypertrophy, as assessed by H&E staining of liver and adipose tissues, were significantly improved by DMDD. CONCLUSION: These data suggest that MDD has potential benefits for the treatment of HFD-induced obesity and insulin resistance, and its effects may be associated with improvements in lipid metabolism and inhibition of the expression of TLR4 in adipose tissues.

Keywords:

2,2,5,5-Tetramethylcyclohexane-1,4-dione,86838-54-2,Natural Products, buy 2,2,5,5-Tetramethylcyclohexane-1,4-dione , 2,2,5,5-Tetramethylcyclohexane-1,4-dione supplier , purchase 2,2,5,5-Tetramethylcyclohexane-1,4-dione , 2,2,5,5-Tetramethylcyclohexane-1,4-dione cost , 2,2,5,5-Tetramethylcyclohexane-1,4-dione manufacturer , order 2,2,5,5-Tetramethylcyclohexane-1,4-dione , high purity 2,2,5,5-Tetramethylcyclohexane-1,4-dione

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: