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5-Benzimidazolecarboxylic acid

CAS# 15788-16-6

5-Benzimidazolecarboxylic acid

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5-Benzimidazolecarboxylic acid: 5mg $17 In Stock
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Chemical structure

5-Benzimidazolecarboxylic acid

3D structure

Chemical Properties of 5-Benzimidazolecarboxylic acid

Cas No. 15788-16-6 SDF Download SDF
PubChem ID 459456 Appearance Powder
Formula C8H6N2O2 M.Wt 162
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3H-benzimidazole-5-carboxylic acid
SMILES C1=CC2=C(C=C1C(=O)O)NC=N2
Standard InChIKey COYPLDIXZODDDL-UHFFFAOYSA-N
Standard InChI InChI=1S/C8H6N2O2/c11-8(12)5-1-2-6-7(3-5)10-4-9-6/h1-4H,(H,9,10)(H,11,12)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

5-Benzimidazolecarboxylic acid Dilution Calculator

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5-Benzimidazolecarboxylic acid Molarity Calculator

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Preparing Stock Solutions of 5-Benzimidazolecarboxylic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.1728 mL 30.8642 mL 61.7284 mL 123.4568 mL 154.321 mL
5 mM 1.2346 mL 6.1728 mL 12.3457 mL 24.6914 mL 30.8642 mL
10 mM 0.6173 mL 3.0864 mL 6.1728 mL 12.3457 mL 15.4321 mL
50 mM 0.1235 mL 0.6173 mL 1.2346 mL 2.4691 mL 3.0864 mL
100 mM 0.0617 mL 0.3086 mL 0.6173 mL 1.2346 mL 1.5432 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 5-Benzimidazolecarboxylic acid

Methods for generation of monoclonal antibodies to the very small drug hapten, 5-benzimidazolecarboxylic acid.[Pubmed:12445730]

J Immunol Methods. 2002 Dec 20;271(1-2):65-75.

Drug-specific monoclonal antibodies (MAbs) were produced against the very small drug hapten (162.15 Da), 5-Benzimidazolecarboxylic acid, an analogue of 2-(4-Thiazolyl)benzimidazole (TBZ) but lacking the thiol group. TBZ is widely used as a broad-spectrum anthelmintic in various animal species and humans and also as a food preservative and agricultural fungicide. The anti-5-Benzimidazolecarboxylic acid antibodies produced have potential use for extraction and/or detection of protein-bound residue forms of TBZ. Three in vivo immunisation regimes (with combinations of two related small drug haptens and two different adjuvants/carrier molecules) and an in vitro immunisation procedure using a combination of three related unconjugated small drug haptens were investigated. Specificity for the hapten immunogen/s was initially determined using two different ELISA procedures. BIACORE analysis, in conjunction with drug binding inhibition studies, was used to confirm the specificity of a small number of selected clones. In vivo immunisation with a drug molecule conjugated to a lipopeptide/T-cell epitope, which acts both as a carrier molecule and an adjuvant was the most useful of the methods tested for the production of specific MAbs to a typically very small hapten with low immunogenic properties.

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