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5'-Methoxylariciresinol

CAS# 105256-12-0

5'-Methoxylariciresinol

Catalog No. BCN7012----Order now to get a substantial discount!

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5'-Methoxylariciresinol: 5mg $903 In Stock
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Quality Control of 5'-Methoxylariciresinol

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Chemical structure

5'-Methoxylariciresinol

3D structure

Chemical Properties of 5'-Methoxylariciresinol

Cas No. 105256-12-0 SDF Download SDF
PubChem ID 184458 Appearance Powder
Formula C21H26O7 M.Wt 390.43
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[(2S,3R,4R)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)oxolan-2-yl]-2,6-dimethoxyphenol
SMILES COC1=CC(=CC(=C1O)OC)C2C(C(CO2)CC3=CC(=C(C=C3)O)OC)CO
Standard InChIKey CRMXIJILTLLGMR-VFCRVFHLSA-N
Standard InChI InChI=1S/C21H26O7/c1-25-17-7-12(4-5-16(17)23)6-14-11-28-21(15(14)10-22)13-8-18(26-2)20(24)19(9-13)27-3/h4-5,7-9,14-15,21-24H,6,10-11H2,1-3H3/t14-,15-,21+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 5'-Methoxylariciresinol

The callus cultures of Stellera chamaejasme.

Biological Activity of 5'-Methoxylariciresinol

Description5'-Methoxylariciresinol is a natural product from Stellera chamaejasme.

Protocol of 5'-Methoxylariciresinol

Structure Identification
Zhongguo Zhong Yao Za Zhi. 2011 Dec;36(24):3457-62.

Studies on chemical constitutes from callus cultures of Stellera chamaejasme.[Pubmed: 22368856]


METHODS AND RESULTS:
From callus cultures of Stellera chamaejasme, 17 compounds were isolated. Based on their physical and chemical data and spectroscopic analysis, they were identified as syringaresinol (1), medioresinol (2), pinoresinol (3), (1R, 2S, 5R, 6S)- 2-(4- hydroxyphenyl)-6-(3-methoxy-4-hydroxyphenyl)-3, 7-dioxabicyclo [3, 3, 0] octane (4), epipinoresinol (5), caruilignan D (6), 3-oxo-guai-4-ene-11, 12-diol (7), (-) -lariciresinol (8), tetrahydro-2-(4-hydroxy-3-methoxyphenyl)-4-[(4-hydroxyphenyl) methyl]-3-furanmethanol (9), 5'-Methoxylariciresinol (10), vladinol D (11), cyclo (L-Pro-L-Val) (12), oxomatairesinol (13), (+) -guayarol (14); acutissimalignan B (15), isolariciresinol (16), and beta-sitosterol (17), respectively.
CONCLUSIONS:
Among these compounds, 12 was a cyclodipeptide, 7 was a sesquiterpene, and the others except 17 were lignans. All compounds were first isolated from callus cultures of S. chamaejasme.

Zhongguo Zhong Yao Za Zhi. 2012 May;37(9):1241-4.

Non-alkaloid chemical constituents from Coptis chinensis.[Pubmed: 22803368]

To separate and identify chemical constituents from Coptis chinensis.
METHODS AND RESULTS:
The compounds were separated and purified by various chromatographic techniques. Their structures were identified on the basis of their physicochemical properties using spectral techniques such as NMR and MS. Thirteen compounds were separated from ethanol extracts of C. chinensis, including seven lignans, three simple phenylpropanoids, two flavones and one phenolic acid, and identified as erythro-guaiacylglycerol-8-O-4'-(coniferyl alcohol) ether (1), threo-guaiacylglycerol-8-O-4'-(coniferyl alcohol) ether (2), (+)-pinoresinol (3), (+)-medioresinol (4), (+)-lariciresinol (5), (+)-5'-Methoxylariciresinol (6), (+)-isolariciresinol (7), chlorogenic acid (8), ferulic acid (9), Z-octadecyl caffeate (10), rhamnetin (11), wogonin (12), and vanillic acid (13).
CONCLUSIONS:
Compounds 1, 2, 4, 6, 10-13 were separated from the genus Coptis for the first time.

5'-Methoxylariciresinol Dilution Calculator

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Preparing Stock Solutions of 5'-Methoxylariciresinol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5613 mL 12.8064 mL 25.6128 mL 51.2256 mL 64.032 mL
5 mM 0.5123 mL 2.5613 mL 5.1226 mL 10.2451 mL 12.8064 mL
10 mM 0.2561 mL 1.2806 mL 2.5613 mL 5.1226 mL 6.4032 mL
50 mM 0.0512 mL 0.2561 mL 0.5123 mL 1.0245 mL 1.2806 mL
100 mM 0.0256 mL 0.1281 mL 0.2561 mL 0.5123 mL 0.6403 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 5'-Methoxylariciresinol

[Non-alkaloid chemical constituents from Coptis chinensis].[Pubmed:22803368]

Zhongguo Zhong Yao Za Zhi. 2012 May;37(9):1241-4.

OBJECTIVE: To separate and identify chemical constituents from Coptis chinensis. METHOD: The compounds were separated and purified by various chromatographic techniques. Their structures were identified on the basis of their physicochemical properties using spectral techniques such as NMR and MS. RESULT: Thirteen compounds were separated from ethanol extracts of C. chinensis, including seven lignans, three simple phenylpropanoids, two flavones and one phenolic acid, and identified as erythro-guaiacylglycerol-8-O-4'-(coniferyl alcohol) ether (1), threo-guaiacylglycerol-8-O-4'-(coniferyl alcohol) ether (2), (+)-pinoresinol (3), (+)-medioresinol (4), (+)-lariciresinol (5), (+)-5'-methoxylariciresinol (6), (+)-isolariciresinol (7), chlorogenic acid (8), ferulic acid (9), Z-octadecyl caffeate (10), rhamnetin (11), wogonin (12), and vanillic acid (13). CONCLUSION: Compounds 1, 2, 4, 6, 10-13 were separated from the genus Coptis for the first time.

[Studies on chemical constitutes from callus cultures of Stellera chamaejasme].[Pubmed:22368856]

Zhongguo Zhong Yao Za Zhi. 2011 Dec;36(24):3457-62.

From callus cultures of Stellera chamaejasme, 17 compounds were isolated. Based on their physical and chemical data and spectroscopic analysis, they were identified as syringaresinol (1), medioresinol (2), pinoresinol (3), (1R, 2S, 5R, 6S)- 2-(4- hydroxyphenyl)-6-(3-methoxy-4-hydroxyphenyl)-3, 7-dioxabicyclo [3, 3, 0] octane (4), epipinoresinol (5), caruilignan D (6), 3-oxo-guai-4-ene-11, 12-diol (7), (-) -lariciresinol (8), tetrahydro-2-(4-hydroxy-3-methoxyphenyl)-4-[(4-hydroxyphenyl) methyl]-3-furanmethanol (9), 5'-methoxylariciresinol (10), vladinol D (11), cyclo (L-Pro-L-Val) (12), oxomatairesinol (13), (+) -guayarol (14); acutissimalignan B (15), isolariciresinol (16), and beta-sitosterol (17), respectively. Among these compounds, 12 was a cyclodipeptide, 7 was a sesquiterpene, and the others except 17 were lignans. All compounds were first isolated from callus cultures of S. chamaejasme.

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