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Agomelatine L(+)-Tartaric acid

CAS# 824393-18-2

Agomelatine L(+)-Tartaric acid

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Agomelatine L(+)-Tartaric acid: 5mg $58 In Stock
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Quality Control of Agomelatine L(+)-Tartaric acid

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Chemical structure

Agomelatine L(+)-Tartaric acid

3D structure

Chemical Properties of Agomelatine L(+)-Tartaric acid

Cas No. 824393-18-2 SDF Download SDF
PubChem ID 78357824 Appearance Powder
Formula C19H23NO8 M.Wt 393.39
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3R)-2,3-dihydroxybutanedioic acid;N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
SMILES CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC.C(C(C(=O)O)O)(C(=O)O)O
Standard InChIKey PJOPJXPTFZIKTL-LREBCSMRSA-N
Standard InChI InChI=1S/C15H17NO2.C4H6O6/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13;5-1(3(7)8)2(6)4(9)10/h3-7,10H,8-9H2,1-2H3,(H,16,17);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Agomelatine L(+)-Tartaric acid Dilution Calculator

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Agomelatine L(+)-Tartaric acid Molarity Calculator

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Preparing Stock Solutions of Agomelatine L(+)-Tartaric acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.542 mL 12.71 mL 25.4201 mL 50.8401 mL 63.5502 mL
5 mM 0.5084 mL 2.542 mL 5.084 mL 10.168 mL 12.71 mL
10 mM 0.2542 mL 1.271 mL 2.542 mL 5.084 mL 6.355 mL
50 mM 0.0508 mL 0.2542 mL 0.5084 mL 1.0168 mL 1.271 mL
100 mM 0.0254 mL 0.1271 mL 0.2542 mL 0.5084 mL 0.6355 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on Agomelatine L(+)-Tartaric acid

Agomelatine (L(+)-Tartaric acid) is a antidepressant, which is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.

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Description

Agomelatine L(+)-Tartaric acid (S-20098 L(+)-Tartaric acid) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. Agomelatine L(+)-Tartaric acid is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively.

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