AlexineCAS# 116174-63-1 |
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| Cas No. | 116174-63-1 | SDF | Download SDF |
| PubChem ID | 189377 | Appearance | Powder |
| Formula | C8H15NO4 | M.Wt | 189.21 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1R,2R,3R,7S,8S)-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,7-triol | ||
| SMILES | C1CN2C(C(C(C2C1O)O)O)CO | ||
| Standard InChIKey | AIQMLBKBQCVDEY-DWOUCZDBSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Alexa leiopetala
| Description | 1. Alexine is a weak inhibitor of glucosidase activity. |
Alexine Dilution Calculator
Alexine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.2851 mL | 26.4257 mL | 52.8513 mL | 105.7027 mL | 132.1283 mL |
| 5 mM | 1.057 mL | 5.2851 mL | 10.5703 mL | 21.1405 mL | 26.4257 mL |
| 10 mM | 0.5285 mL | 2.6426 mL | 5.2851 mL | 10.5703 mL | 13.2128 mL |
| 50 mM | 0.1057 mL | 0.5285 mL | 1.057 mL | 2.1141 mL | 2.6426 mL |
| 100 mM | 0.0529 mL | 0.2643 mL | 0.5285 mL | 1.057 mL | 1.3213 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Asymmetric total synthesis of natural pyrrolizidine alkaloid, (+)-alexine
Tetrahedron Letters,2000,41(40): 7661-5.
The total synthesis of the potent glycosidase inhibitor (+)-Alexine with five contiguous stereogenic centres [(1R,2R,3R,7S,7aS)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine alkaloid] is described featuring the efficient and stereodefined novel elaboration of the functionalized homochiral lactam derived from 2,3,5-tri-O-benzyl-β-d-arabinofuranose.
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