AndrostadienedioneCAS# 897-06-3 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 897-06-3 | SDF | Download SDF |
| PubChem ID | 13472 | Appearance | Powder |
| Formula | C19H24O2 | M.Wt | 284.4 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione | ||
| SMILES | CC12CCC3C(C1CCC2=O)CCC4=CC(=O)C=CC34C | ||
| Standard InChIKey | LUJVUUWNAPIQQI-QAGGRKNESA-N | ||
| Standard InChI | InChI=1S/C19H24O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-16H,3-6,8,10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Androstadienedione Dilution Calculator
Androstadienedione Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.5162 mL | 17.5809 mL | 35.1617 mL | 70.3235 mL | 87.9044 mL |
| 5 mM | 0.7032 mL | 3.5162 mL | 7.0323 mL | 14.0647 mL | 17.5809 mL |
| 10 mM | 0.3516 mL | 1.7581 mL | 3.5162 mL | 7.0323 mL | 8.7904 mL |
| 50 mM | 0.0703 mL | 0.3516 mL | 0.7032 mL | 1.4065 mL | 1.7581 mL |
| 100 mM | 0.0352 mL | 0.1758 mL | 0.3516 mL | 0.7032 mL | 0.879 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Bioconversion of Phytosterols into Androstadienedione by Mycobacterium smegmatis CECT 8331.[Pubmed:28710631]
Methods Mol Biol. 2017;1645:211-225.
The C19 steroid 1,4-androstadiene-3,17-dione (Androstadienedione, ADD) is an added value product used as a synthon in the pharmaceutical industry for the commercial production of corticosteroids, mineralocorticoids, oral contraceptives, and other pharmaceutical steroids. Phytosterol biotransformation catalyzed by microbial whole cells is actually a very well-established research area in white biotechnology. The protocol below provides detailed information on ADD production by the mutant CECT 8331 of Mycobacterium smegmatis mc(2)155 using phytosterols as raw material in a lab scale. This protocol describes the bioconversion of phytosterols into ADD in a single fermentation step.
Effects of Different Carbon Sources on Growth, Membrane Permeability, beta-Sitosterol Consumption, Androstadienedione and Androstenedione Production by Mycobacterium neoaurum.[Pubmed:26298579]
Interdiscip Sci. 2016 Mar;8(1):102-7.
Effects of different carbon sources on growth, membrane permeability, beta-sitosterol consumption, Androstadienedione and androstenedione (AD(D)) production by Mycobacterium neoaurum were investigated. The results indicated that glucose was advantageous to the growth and resulted in the adverse effects on the phytosterols consumption and AD(D) production compared to the results of propanol and isopropanol as sole carbon source. The cell wall widths of 9.76 by propanol and 8.00 nm by isopropanol were 38.3 and 49.4 % thinner than that of 15.82 nm by glucose, respectively. The partition coefficient of the cell grown in propanol and isopropanol was 18.1 and 22.2, which were 7.23- and 9.09-fold higher than that of the cell grown in glucose.
