AquilegiolideCAS# 94481-79-5 |
- Menisdaurilide
Catalog No.:BCN9603
CAS No.:67765-59-7
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 94481-79-5 | SDF | Download SDF |
| PubChem ID | 185347 | Appearance | Powder |
| Formula | C8H8O3 | M.Wt | 152.15 |
| Type of Compound | Other NPs | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (6S,7aS)-6-hydroxy-7,7a-dihydro-6H-1-benzofuran-2-one | ||
| SMILES | C1C(C=CC2=CC(=O)OC21)O | ||
| Standard InChIKey | RAXNUTINVDSFEU-RQJHMYQMSA-N | ||
| Standard InChI | InChI=1S/C8H8O3/c9-6-2-1-5-3-8(10)11-7(5)4-6/h1-3,6-7,9H,4H2/t6-,7+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Aquilegiolide Dilution Calculator
Aquilegiolide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 6.5725 mL | 32.8623 mL | 65.7246 mL | 131.4492 mL | 164.3115 mL |
| 5 mM | 1.3145 mL | 6.5725 mL | 13.1449 mL | 26.2898 mL | 32.8623 mL |
| 10 mM | 0.6572 mL | 3.2862 mL | 6.5725 mL | 13.1449 mL | 16.4312 mL |
| 50 mM | 0.1314 mL | 0.6572 mL | 1.3145 mL | 2.629 mL | 3.2862 mL |
| 100 mM | 0.0657 mL | 0.3286 mL | 0.6572 mL | 1.3145 mL | 1.6431 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Isolation, characterization and HPLC quantification of compounds from Aquilegia fragrans Benth: Their in vitro antibacterial activities against bovine mastitis pathogens.[Pubmed:26631757]
J Ethnopharmacol. 2016 Feb 3;178:9-12.
ETHNO-PHARMACOLOGICAL RELEVANCE: The underground parts of Aquilegia fragrans are traditionally used for the treatment of wounds and various inflammatory diseases like bovine mastitis. However, there are no reports on the phytochemical characterization and antibacterial studies of A. fragrans. AIM OF THE STUDY: To isolate compounds from the methanol extract of the underground parts of A. fragrans and determine their antibacterial activity against the pathogens of bovine mastitis. The study was undertaken in order to scientifically validate the traditional use of A. fragrans. MATERIALS AND METHODS: Five compounds were isolated from the methanol extract of the underground parts of A. fragrans using silica gel column chromatography. Structural elucidation of the isolated compounds was done using spectral data analysis and comparison with literature. High performance liquid chromatography (HPLC) was used for the qualitative and quantitative determination of isolated compounds in the crude methanol extract. The methanol extract and isolated compounds were evaluated for antibacterial activities against mastitis pathogens using broth micro-dilution technique. RESULTS: The five isolated compounds were identified as (1) 2, 4-dihydroxyphenylacetic acid methyl ester (2) beta-sitosterol (3) Aquilegiolide (4) Glochidionolactone-A and (5) Magnoflorine. A quick and sensitive HPLC method was developed for the first time for qualitative and quantitative determination of four isolated marker compounds from A. fragrans. The crude methanol extract and compound 5 exhibited weak antibacterial activities that varied between the bacterial species (MIC=500-3000 microg/ml). CONCLUSIONS: The above results show that the crude methanol extract and isolated compounds from A. fragrans exhibit weak antibacterial activities. Further phytochemical and pharmacological studies are required for proper scientific validation of the folk use of this plant species in the treatment of various inflammatory diseases like bovine mastitis.
[Study on Chemical Constituents from Hypocotyls of Mangrove Bruguiera gymnorrhiza].[Pubmed:26214874]
Zhong Yao Cai. 2015 Jan;38(1):85-8.
OBJECTIVE: To study the chemical constituents from the hypocotyls of mangrove Bruguiera gymnorrhiza. METHODS: The chemical constituents were isolated and purified by recrystallization, silica gel column chromatography and semi-preparative HPLC. Their structures were identified by spectroscopic analysis and comparison with literatures. RESULTS: Seven compounds were isolated and their structures were identified as 3-beta-(Z)-coumaroyllupeol (1), dioslupecin (2), cholesterol (3), menisdaurillide (4), Aquilegiolide (5) vomifoliol (6) and roseoside II (7). CONCLUSION: Compounds 1,2 and 4 - 7 are isolated from this plant for the first time.
Discovery of the apoptosis-inducing activity and high accumulation of the butenolides, menisdaurilide and aquilegiolide in Dicentra spectabilis.[Pubmed:17999351]
Planta Med. 2007 Dec;73(15):1543-47.
The occurrence of two butenolides, menisdaurilide and Aquilegiolide, in commercial specimens of Dicentra spectabilis is reported for the first time; a rapid and direct isolation protocol is described. The ability of these lactones to induce apoptosis in human tumour cell lines at 10 microM concentration is also described. The high abundance and apoptosis-inducing activity reported here indicates that these constituents play a more significant role than the hormonal action previously attributed to them.
7,8-Dihydrobenzofuranones from Ouratea reticulata.[Pubmed:11543976]
Fitoterapia. 2001 Aug;72(6):706-8.
Two known 7,8-dihydrobenzofuranones, Aquilegiolide (1) and menisdaurilide (2), were isolated from Ouratea reticulata root bark.
