Cistanoside F

CAS# 97411-47-7

Cistanoside F

Catalog No. BCN8549----Order now to get a substantial discount!

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Cistanoside F: 5mg Please Inquire In Stock
Cistanoside F: 10mg Please Inquire In Stock
Cistanoside F: 20mg Please Inquire Please Inquire
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Quality Control of Cistanoside F

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Chemical structure

Cistanoside F

3D structure

Chemical Properties of Cistanoside F

Cas No. 97411-47-7 SDF Download SDF
PubChem ID 101688189 Appearance Powder
Formula C21H28O13 M.Wt 488.44
Type of Compound Phenylpropanoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(2R,3R,4R,5R)-1,2,5-trihydroxy-6-oxo-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyhexan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
SMILES CC1C(C(C(C(O1)OC(C(C=O)O)C(C(CO)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O)O
Standard InChIKey KARNWFDIYRKBOE-BHSPTIPFSA-N
Standard InChI InChI=1S/C21H28O13/c1-9-16(29)17(30)18(31)21(32-9)34-20(14(27)8-23)19(13(26)7-22)33-15(28)5-3-10-2-4-11(24)12(25)6-10/h2-6,8-9,13-14,16-22,24-27,29-31H,7H2,1H3/b5-3+/t9-,13+,14-,16-,17+,18+,19+,20+,21-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cistanoside F

The herbs of Cistanche deserticola Ma

Biological Activity of Cistanoside F

Description1. Cistanoside F shows vasorelaxant activity. 2. Cistanoside F has antioxidative effect, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide anion radical (O2-.).
TargetsNADPH-oxidase

Cistanoside F Dilution Calculator

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Cistanoside F Molarity Calculator

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Preparing Stock Solutions of Cistanoside F

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0473 mL 10.2367 mL 20.4733 mL 40.9467 mL 51.1834 mL
5 mM 0.4095 mL 2.0473 mL 4.0947 mL 8.1893 mL 10.2367 mL
10 mM 0.2047 mL 1.0237 mL 2.0473 mL 4.0947 mL 5.1183 mL
50 mM 0.0409 mL 0.2047 mL 0.4095 mL 0.8189 mL 1.0237 mL
100 mM 0.0205 mL 0.1024 mL 0.2047 mL 0.4095 mL 0.5118 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Cistanoside F

A new iridoid from Adenosma caeruleum R. Br.[Pubmed:19442709]

Fitoterapia. 2009 Sep;80(6):358-60.

A new iridoid glycoside, adenosmoside, together with five known phenylpropanoids, crenatoside, verbascoside, Cistanoside F, campneoside I, and campneoside II and two known flavonoids, apigenin 7-O-beta-D-glucuronopyranoside and apigenin 7-O-beta-D-glucopyranoside, were isolated from the aerial parts of Adenosma caeruleum R. Br. Their structures were elucidated by spectral evidence.

Phenylethanoid oligoglycosides and acylated oligosugars with vasorelaxant activity from Cistanche tubulosa.[Pubmed:16908167]

Bioorg Med Chem. 2006 Nov 15;14(22):7468-75.

The methanolic extract from the dried stems of Cistanche tubulosa (Schrenk) R. Wight was found to show an inhibitory effect on contractions induced by noradrenaline in isolated rat aortic strips. From the extract, new phenylethanoid oligoglycoside constituents, kankanosides F and G, and an acylated oligosugar, kankanose, were isolated together with 14 known compounds. The structures of these new compounds were determined on the basis of their chemical and physicochemical evidence. In addition, principal constituents, kankanoside F, kankanose, echinacoside, acteoside, and Cistanoside F, showed vasorelaxant activity, and several structural requirements for the activity were clarified.

Antioxidative effects of phenylethanoids from Cistanche deserticola.[Pubmed:8996643]

Biol Pharm Bull. 1996 Dec;19(12):1580-5.

The acetone-H2O (9:1) extract from the stem of Cistanche deserticola showed a strong free radical scavenging activity. Nine major phenylethanoid compounds were isolated from this extract. They were identified by NMR as acteoside, isoacteoside, 2'-acetylacteoside, tubuloside B, echinacoside, tubuloside A, syringalide A 3'-alpha-rhamnopyranoside, cistanoside A and Cistanoside F. All of these compounds showed stronger free radical scavenging activities than alpha-tocopherol on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide anion radical (O2-.). Among the nine compounds, isoacteoside and tubuloside B, whose caffeoyl moiety is at 6'-position of the glucose, showed an inhibitory effect on XOD. We further studied the effects of these phenylethanoids on the lipid peroxidation in rat liver microsomes induced by enzymatic and non-enzymatic methods. As expected, each of them exhibited significant inhibition on both ascorbic acid/Fe2+ and ADP/NADPH/Fe3+ induced lipid peroxidation in rat liver microsomes, which were more potent than alpha-tocopherol of caffeic acid. The antioxidative effect was found to be potentiated by an increase in the number of phenolic hydroxyl groups in the molecule.

Description

Cistanoside F is a phenylethanoid glycosid isolated from Cistanche deserticola, with antioxidative effect.

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