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Curcumaromin C

CAS# 1810034-40-2

Curcumaromin C

2D Structure

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3D structure

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Curcumaromin C

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Chemical Properties of Curcumaromin C

Cas No. 1810034-40-2 SDF Download SDF
PubChem ID 125181871 Appearance Powder
Formula C29H32O4 M.Wt 444.57
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1E,6E)-1,7-bis(4-hydroxyphenyl)-4-[(1R,6R)-3-methyl-6-propan-2-ylcyclohex-2-en-1-yl]hepta-1,6-diene-3,5-dione
SMILES CC1=CC(C(CC1)C(C)C)C(C(=O)C=CC2=CC=C(C=C2)O)C(=O)C=CC3=CC=C(C=C3)O
Standard InChIKey XPEWDUSWUQJRDO-WUDRIEKWSA-N
Standard InChI InChI=1S/C29H32O4/c1-19(2)25-15-4-20(3)18-26(25)29(27(32)16-9-21-5-11-23(30)12-6-21)28(33)17-10-22-7-13-24(31)14-8-22/h5-14,16-19,25-26,29-31H,4,15H2,1-3H3/b16-9+,17-10+/t25-,26+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Curcumaromin C

The herbs of Curcuma aromatica Salisb.

Biological Activity of Curcumaromin C

DescriptionCurcumaromin C is a natural product from Curcuma aromatica Salisb.

Protocol of Curcumaromin C

Structure Identification
Helvetica Chimica Acta, 2015, 98(9):1325-1331.

Curcumaromins A, B, and C, Three Novel Curcuminoids from Curcuma aromatica.[Reference: WebLink]


METHODS AND RESULTS:
Three novel curcuminoids, Curcumaromin A, curcumaromin B, Curcumaromin C (1-3, resp.), along with a known compound, longiferone B (4) were isolated from Curcuma aromatica Salisb. The structures of the new compounds were elucidated as (1E,4Z,6E)-5-hydroxy-7-{4-hydroxy-3-[(1R ,6R )-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-yl)phenyl}-1-(4-hydroxyphenyl)hepta-1,4,6-trien-3-one (1), 2,3-dihydro-2-(4-hydroxyphenyl)-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-[(1R ,6R )-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-yl]-4H-pyran-4-one (2), and (1E,6E)-1,7-bis(4-hydroxyphenyl)-4-[(1R ,6R )-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-yl]hepta-1,6-diene-3,5-dione (3) on the basis of spectroscopic analysis.
CONCLUSIONS:
Curcumaromin A, curcumaromin B, Curcumaromin C (1-3) represented the first examples of menthane monoterpene-coupled curcuminoids. The known compound, longiferone B (4), was the first daucane sesquiterpene isolated from the genus Curcuma.

Curcumaromin C Dilution Calculator

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Preparing Stock Solutions of Curcumaromin C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2494 mL 11.2468 mL 22.4936 mL 44.9873 mL 56.2341 mL
5 mM 0.4499 mL 2.2494 mL 4.4987 mL 8.9975 mL 11.2468 mL
10 mM 0.2249 mL 1.1247 mL 2.2494 mL 4.4987 mL 5.6234 mL
50 mM 0.045 mL 0.2249 mL 0.4499 mL 0.8997 mL 1.1247 mL
100 mM 0.0225 mL 0.1125 mL 0.2249 mL 0.4499 mL 0.5623 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Curcumaromin C

Curcumaromins A, B, and C, Three Novel Curcuminoids from Curcuma aromatica.

Helvetica Chimica Acta, 2015, 98(9):1325-1331.

Three novel curcuminoids, curcumaromin A, curcumaromin B, Curcumaromin C (1-3, resp.), along with a known compound, longiferone B (4) were isolated from Curcuma aromatica Salisb. The structures of the new compounds were elucidated as (1E,4Z,6E)-5-hydroxy-7-{4-hydroxy-3-[(1R ,6R )-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-yl)phenyl}-1-(4-hydroxyphenyl)hepta-1,4,6-trien-3-one (1), 2,3-dihydro-2-(4-hydroxyphenyl)-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-[(1R ,6R )-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-yl]-4H-pyran-4-one (2), and (1E,6E)-1,7-bis(4-hydroxyphenyl)-4-[(1R ,6R )-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-yl]hepta-1,6-diene-3,5-dione (3) on the basis of spectroscopic analysis. Curcumaromin A, curcumaromin B, Curcumaromin C (1-3) represented the first examples of menthane monoterpene-coupled curcuminoids. The known compound, longiferone B (4), was the first daucane sesquiterpene isolated from the genus Curcuma.

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