Cyclo(Leu-Leu)

CAS# 1436-27-7

Cyclo(Leu-Leu)

2D Structure

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Cyclo(Leu-Leu): 5mg $196 In Stock
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Quality Control of Cyclo(Leu-Leu)

3D structure

Package In Stock

Cyclo(Leu-Leu)

Number of papers citing our products

Chemical Properties of Cyclo(Leu-Leu)

Cas No. 1436-27-7 SDF Download SDF
PubChem ID 137006 Appearance Powder
Formula C12H22N2O2 M.Wt 226.32
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3,6-bis(2-methylpropyl)piperazine-2,5-dione
SMILES CC(C)CC1C(=O)NC(C(=O)N1)CC(C)C
Standard InChIKey XWYXUMDVQIOAPR-UHFFFAOYSA-N
Standard InChI InChI=1S/C12H22N2O2/c1-7(2)5-9-11(15)14-10(6-8(3)4)12(16)13-9/h7-10H,5-6H2,1-4H3,(H,13,16)(H,14,15)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cyclo(Leu-Leu)

The Pantoea agglomerans

Biological Activity of Cyclo(Leu-Leu)

DescriptionCyclo(Leu-Leu) is an efficient supramolecular catalyst.

Protocol of Cyclo(Leu-Leu)

Structure Identification
Supramolecular Chemistry, 2017,29(5):330- 49.

Interfacial supramolecular biomimetic epoxidation catalysed by cyclic dipeptides[Reference: WebLink]


METHODS AND RESULTS:
We synthesised a library of cis- and trans-cyclic dipeptides and evaluated their efficacy as catalysts in the asymmetric Weitz-Scheffer epoxidation of trans-chalcone. A thorough investigation relying on structure-activity studies and computational studies provided insights into the mechanism of the process. Our results revealed some structural features required for efficient conversion and for introduction of chirality into the product. The cyclic dipeptide acts as a catalyst by templating a supramolecular arrangement at the aqueous-organic interface required for efficient transformations to occur.
CONCLUSIONS:
Among all cyclic dipeptides investigated, Cyclo(Leu-Leu) was the most efficient supramolecular catalyst.

Cyclo(Leu-Leu) Dilution Calculator

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Cyclo(Leu-Leu) Molarity Calculator

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Preparing Stock Solutions of Cyclo(Leu-Leu)

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4185 mL 22.0926 mL 44.1852 mL 88.3704 mL 110.4631 mL
5 mM 0.8837 mL 4.4185 mL 8.837 mL 17.6741 mL 22.0926 mL
10 mM 0.4419 mL 2.2093 mL 4.4185 mL 8.837 mL 11.0463 mL
50 mM 0.0884 mL 0.4419 mL 0.8837 mL 1.7674 mL 2.2093 mL
100 mM 0.0442 mL 0.2209 mL 0.4419 mL 0.8837 mL 1.1046 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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