Cyclo(Leu-Val)

CAS# 5625-50-3

Cyclo(Leu-Val)

2D Structure

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Cyclo(Leu-Val): 5mg $127 In Stock
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Quality Control of Cyclo(Leu-Val)

3D structure

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Cyclo(Leu-Val)

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Chemical Properties of Cyclo(Leu-Val)

Cas No. 5625-50-3 SDF Download SDF
PubChem ID 138543 Appearance Powder
Formula C11H20N2O2 M.Wt 212.29
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3-(2-methylpropyl)-6-propan-2-ylpiperazine-2,5-dione
SMILES CC(C)CC1C(=O)NC(C(=O)N1)C(C)C
Standard InChIKey UPOUGDHEEGKEGS-UHFFFAOYSA-N
Standard InChI InChI=1S/C11H20N2O2/c1-6(2)5-8-10(14)13-9(7(3)4)11(15)12-8/h6-9H,5H2,1-4H3,(H,12,15)(H,13,14)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cyclo(Leu-Val)

The roots of Panax notoginseng (Burk.)F.H.Chen

Biological Activity of Cyclo(Leu-Val)

DescriptionCyclo(Leu-Val) is a cyclic dipeptide from the fermentation broth of F8712 strain.
In vitro

Bioactive cyclodipeptides extracted from marine microbes in East China Sea[Reference: WebLink]

《Academic Journal of Second Military Medical University》 2006-01

To search for bioactive compounds from marine microbes.
METHODS AND RESULTS:
Pyricularia oryzae was used to screen microbes.Compounds extracted with EtOAc from the fermentation broth of F8712 strain(an active microbe screened out) were separated.The chemical structures of the separated compounds were identified by ~(1)HNMR,~(13)CNMR and ESI-MS techniques. Six cyclic dipeptides,cyclo(Ala-Leu),cyclo(Ala-Ile),cyclo(Ile-Pro),cyclo(Val-Pro),cyclo(Leu-Pro) and Cyclo(Leu-Val),were obtained.
CONCLUSIONS:
: None of the 6 cyclodipeptides has any anti-Pyricularia oryzae activities.Compound Ⅴ has potent inhibitory effects on Vibrio anguillarm with a minimum inhibitory concentration of 0.07 μg/ml.

Cyclo(Leu-Val) Dilution Calculator

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Cyclo(Leu-Val) Molarity Calculator

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Preparing Stock Solutions of Cyclo(Leu-Val)

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7105 mL 23.5527 mL 47.1054 mL 94.2107 mL 117.7634 mL
5 mM 0.9421 mL 4.7105 mL 9.4211 mL 18.8421 mL 23.5527 mL
10 mM 0.4711 mL 2.3553 mL 4.7105 mL 9.4211 mL 11.7763 mL
50 mM 0.0942 mL 0.4711 mL 0.9421 mL 1.8842 mL 2.3553 mL
100 mM 0.0471 mL 0.2355 mL 0.4711 mL 0.9421 mL 1.1776 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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