Glyurallin A

CAS# 199331-36-7

Glyurallin A

Catalog No. BCN7538----Order now to get a substantial discount!

Product Name & Size Price Stock
Glyurallin A: 5mg $1098 In Stock
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Quality Control of Glyurallin A

Number of papers citing our products

Chemical structure

Glyurallin A

3D structure

Chemical Properties of Glyurallin A

Cas No. 199331-36-7 SDF Download SDF
PubChem ID 15818598 Appearance Powder
Formula C21H20O5 M.Wt 352.38
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-methoxy-2-(3-methylbut-2-enyl)-6H-[1]benzofuro[3,2-c]chromene-3,9-diol
SMILES CC(=CCC1=C(C=C2C(=C1OC)C3=C(CO2)C4=C(O3)C=C(C=C4)O)O)C
Standard InChIKey AEAIWNGAMDGGNB-UHFFFAOYSA-N
Standard InChI InChI=1S/C21H20O5/c1-11(2)4-6-14-16(23)9-18-19(20(14)24-3)21-15(10-25-18)13-7-5-12(22)8-17(13)26-21/h4-5,7-9,22-23H,6,10H2,1-3H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Glyurallin A

The roots of Glycyrrhiza aspera.

Biological Activity of Glyurallin A

Description1. Glyurallin A possesses an antigenotoxic effect against carcinogenic N-methyl-N-nitrosourea (MNU) for the first time, it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.

Glyurallin A Dilution Calculator

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Glyurallin A Molarity Calculator

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Preparing Stock Solutions of Glyurallin A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8378 mL 14.1892 mL 28.3785 mL 56.7569 mL 70.9461 mL
5 mM 0.5676 mL 2.8378 mL 5.6757 mL 11.3514 mL 14.1892 mL
10 mM 0.2838 mL 1.4189 mL 2.8378 mL 5.6757 mL 7.0946 mL
50 mM 0.0568 mL 0.2838 mL 0.5676 mL 1.1351 mL 1.4189 mL
100 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.5676 mL 0.7095 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Glyurallin A

Isolation and characterization of antimutagenic components of Glycyrrhiza aspera against N-methyl-N-nitrosourea.[Pubmed:28074112]

Genes Environ. 2017 Jan 6;39:5.

BACKGROUND: A powdered ethanolic extract of Glycyrrhiza aspera root exhibits antimutagenic activity against N-methyl-N-nitrosourea (MNU) based on the Ames assay with Salmonella typhimurium TA1535. The aim of this study was to identify the antimutagenic components of the powdered ethanolic extract of G. aspera root. RESULTS: The powdered ethanolic extract of G. aspera root was sequentially suspended in n-hexane, carbon tetrachloride, dichloromethane, ethyl acetate, and ethanol, and each solvent soluble fraction and the residue were assayed for antimutagenic activity against MNU in S. typhimurium TA1535. The dichloromethane soluble fraction exhibited the highest antimutagenicity and was fractionated several times by silica gel chromatography. The fraction with the highest antimutagenic activity was further purified using HPLC, and the fractions were assayed for antimutagenicity against MNU in S. typhimurium TA1535. Finally, five components with antimutagenic activity against MNU were identified as Glyurallin A, glyasperin B, licoricidin, 1-methoxyphaseollin, and licoisoflavone B. CONCLUSIONS: The five components were demonstrated to possess an antigenotoxic effect against carcinogenic MNU for the first time. It is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.

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