Hopeyhopin

CAS# 63975-56-4

Hopeyhopin

Catalog No. BCN7533----Order now to get a substantial discount!

Product Name & Size Price Stock
Hopeyhopin: 5mg $828 In Stock
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Quality Control of Hopeyhopin

Number of papers citing our products

Chemical structure

Hopeyhopin

3D structure

Chemical Properties of Hopeyhopin

Cas No. 63975-56-4 SDF Download SDF
PubChem ID 609122 Appearance Powder
Formula C15H14O5 M.Wt 274.27
Type of Compound Coumarins Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6-(3,3-dimethyloxirane-2-carbonyl)-7-methoxychromen-2-one
SMILES CC1(C(O1)C(=O)C2=C(C=C3C(=C2)C=CC(=O)O3)OC)C
Standard InChIKey VFKJAXDQCDDPCK-UHFFFAOYSA-N
Standard InChI InChI=1S/C15H14O5/c1-15(2)14(20-15)13(17)9-6-8-4-5-12(16)19-10(8)7-11(9)18-3/h4-7,14H,1-3H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Hopeyhopin

The herbs of Micromelum falcatum.

Biological Activity of Hopeyhopin

DescriptionHopeyhopin is a natural product from Micromelum falcatum.
In vitro

Benzene, coumarin and quinolinone derivatives from roots of Citrus hystrix.[Pubmed: 23352239 ]

Phytochemistry. 2013 Apr;88:79-84.


METHODS AND RESULTS:
Two coumarins, hystrixarin (1) and (+)-Hopeyhopin (2); a benzenoid derivative, hystroxene-I (3) and a quinolinone alkaloid, hystrolinone (4), along with 33 known compounds were isolated from the crude acetone extract of the roots of Citrus hystrix.
CONCLUSIONS:
Their structures were determined by analysis of 1D and 2D NMR spectroscopic data. The antioxidant, anti-HIV and antibacterial activities of the isolated compounds were also evaluated.

Protocol of Hopeyhopin

Structure Identification
Zhong Yao Cai. 2013 May;36(5):744-6.

Study on the chemical constituents from ethyl acetate extract of Micromelum falcatum.[Pubmed: 24218965]

To study the chemical constituents from ethyl acetate extract of Micromelum falcatum.
METHODS AND RESULTS:
The constituents were separated and purified by silica gel, Sephadex LH-20 and HPLC. Their structures were elucidated by spectral analysis (NMR, MS). Ten compounds were isolated and identified as micropubescin (1), phebalosin (2), scopoletin (3), citrubuntin (4), thamnosmonin (5), Hopeyhopin (6), arnottinin (7), casegravol (8), 2-methoxy-5-hydroxy cinnamate (9), threo-syringoylglycerol (10).
CONCLUSIONS:
Compounds 1 - 10 are obtained from this plant for the first time.

Hopeyhopin Dilution Calculator

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Hopeyhopin Molarity Calculator

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Preparing Stock Solutions of Hopeyhopin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.646 mL 18.2302 mL 36.4604 mL 72.9208 mL 91.1511 mL
5 mM 0.7292 mL 3.646 mL 7.2921 mL 14.5842 mL 18.2302 mL
10 mM 0.3646 mL 1.823 mL 3.646 mL 7.2921 mL 9.1151 mL
50 mM 0.0729 mL 0.3646 mL 0.7292 mL 1.4584 mL 1.823 mL
100 mM 0.0365 mL 0.1823 mL 0.3646 mL 0.7292 mL 0.9115 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Hopeyhopin

[Study on the chemical constituents from ethyl acetate extract of Micromelum falcatum].[Pubmed:24218965]

Zhong Yao Cai. 2013 May;36(5):744-6.

OBJECTIVE: To study the chemical constituents from ethyl acetate extract of Micromelum falcatum. METHODS: The constituents were separated and purified by silica gel, Sephadex LH-20 and HPLC. Their structures were elucidated by spectral analysis (NMR, MS). RESULTS: Ten compounds were isolated and identified as micropubescin (1), phebalosin (2), scopoletin (3), citrubuntin (4), thamnosmonin (5), Hopeyhopin (6), arnottinin (7), casegravol (8), 2-methoxy-5-hydroxy cinnamate (9), threo-syringoylglycerol (10). CONCLUSION: Compounds 1 - 10 are obtained from this plant for the first time.

Benzene, coumarin and quinolinone derivatives from roots of Citrus hystrix.[Pubmed:23352239]

Phytochemistry. 2013 Apr;88:79-84.

Two coumarins, hystrixarin (1) and (+)-Hopeyhopin (2); a benzenoid derivative, hystroxene-I (3) and a quinolinone alkaloid, hystrolinone (4), along with 33 known compounds were isolated from the crude acetone extract of the roots of Citrus hystrix. Their structures were determined by analysis of 1D and 2D NMR spectroscopic data. The antioxidant, anti-HIV and antibacterial activities of the isolated compounds were also evaluated.

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