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Ropivacaine mesylate

CAS# 854056-07-8

Ropivacaine mesylate

2D Structure

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Ropivacaine mesylate: 5mg $17 In Stock
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Quality Control of Ropivacaine mesylate

3D structure

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Ropivacaine mesylate

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Chemical Properties of Ropivacaine mesylate

Cas No. 854056-07-8 SDF Download SDF
PubChem ID 24784155 Appearance Powder
Formula C18H30N2O4S M.Wt 370.5
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;methanesulfonic acid
SMILES CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.CS(=O)(=O)O
Standard InChIKey YPTSIOMXZOPKAF-RSAXXLAASA-N
Standard InChI InChI=1S/C17H26N2O.CH4O3S/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;1-5(2,3)4/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H3,(H,2,3,4)/t15-;/m0./s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Ropivacaine mesylate Dilution Calculator

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Ropivacaine mesylate Molarity Calculator

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Preparing Stock Solutions of Ropivacaine mesylate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6991 mL 13.4953 mL 26.9906 mL 53.9811 mL 67.4764 mL
5 mM 0.5398 mL 2.6991 mL 5.3981 mL 10.7962 mL 13.4953 mL
10 mM 0.2699 mL 1.3495 mL 2.6991 mL 5.3981 mL 6.7476 mL
50 mM 0.054 mL 0.2699 mL 0.5398 mL 1.0796 mL 1.3495 mL
100 mM 0.027 mL 0.135 mL 0.2699 mL 0.5398 mL 0.6748 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ropivacaine mesylate

[Clinical effectiveness of ropivacaine mesylate in epidural anesthesia and postoperative analgesia].[Pubmed:15663236]

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Dec;26(6):700-3.

OBJECTIVE: To compare the clinical effectiveness of Ropivacaine mesylate and ropivacaine hydrochloride in epidural anesthesia and postoperative analgesia. METHODS: Forty-four patients undergoing epidural anesthesia for intraperitoneal hysterectomy or hysteromyomectomy were randomly assigned to two equal groups. Group ropivacaine hydrochloride received 15 ml ropivacaine hydrochloride of 7.5 mg/ml in anesthetic and 2 mg/ml in postoperative analgesic subsequently while group Ropivacaine mesylate correspondingly received Ropivacaine mesylate of both 15 ml of 8.94 mg/ml and 2.374 mg/ml. RESULTS: No significant differences were found in the onset, extent, and duration of sensory and motor blockage, and also in the hemodynamic stability, when Ropivacaine mesylate was comparable with ropivacaine hydrochloride. No severe adverse events were observed in this study. CONCLUSION: Ropivacaine mesylate is an effective and safe alternative to ropivacaine hydrochloride in epidural anesthesia and postoperative analgesia.

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