Securinol A

CAS# 5008-48-0

Securinol A

2D Structure

Catalog No. BCN6987----Order now to get a substantial discount!

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Securinol A

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Chemical Properties of Securinol A

Cas No. 5008-48-0 SDF Download SDF
PubChem ID 124355873 Appearance Powder
Formula C13H17NO3 M.Wt 235.28
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,2R,8S,15R)-15-hydroxy-13-oxa-7-azatetracyclo[6.5.2.01,10.02,7]pentadec-10-en-12-one
SMILES C1CCN2C(C1)C34CC(C2CC3=CC(=O)O4)O
Standard InChIKey SVHWKXNNRMAUAN-SBFPOUOMSA-N
Standard InChI InChI=1S/C13H17NO3/c15-10-7-13-8(6-12(16)17-13)5-9(10)14-4-2-1-3-11(13)14/h6,9-11,15H,1-5,7H2/t9-,10+,11+,13+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Securinol A

The leaves and twigs of Securinega suffruticosa.

Biological Activity of Securinol A

DescriptionSecurinol A is a natural product from Securinega suffruticosa.

Protocol of Securinol A

Structure Identification
Chinese Journal of Natural Medicines, 2006, 4(4):260-263.

Chemical constituents of Securinega suffruticosa.[Reference: WebLink]

To investigate the chemical constituents of the leaves and twigs of Securinega suffruticosa (Pall.) Rehd.
METHODS AND RESULTS:
Column chromatographic methods were used to separate the chemical constituents whose structures were elucidated by means of physicochemical properties and spectral analysis. Eleven compounds were isolated and identified as (-)-15β-ethoxy-14,15-dihydroviroallosecurinine (1), securinine (2), 14,15-dihydrosecurinine (3), 4-epiphyllanthine (4), Securitinine (5), viroallosecurinine (6), Securinol A (7), secu' amamine A (8), ent-phyllanthidine (9), ( )-aquilegiolide (10) and ( )-menisdaurilide (11), respectively.
CONCLUSIONS:
Compound 1 is a novel compound. Compounds 4, 8, 10 and 11 were isolated from Securinega suffruticosa for the first time.

Securinol A Dilution Calculator

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Preparing Stock Solutions of Securinol A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.2503 mL 21.2513 mL 42.5026 mL 85.0051 mL 106.2564 mL
5 mM 0.8501 mL 4.2503 mL 8.5005 mL 17.001 mL 21.2513 mL
10 mM 0.425 mL 2.1251 mL 4.2503 mL 8.5005 mL 10.6256 mL
50 mM 0.085 mL 0.425 mL 0.8501 mL 1.7001 mL 2.1251 mL
100 mM 0.0425 mL 0.2125 mL 0.425 mL 0.8501 mL 1.0626 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Securinol A

Chemical constituents of Securinega suffruticosa.

Chinese Journal of Natural Medicines, 2006, 4(4):260-263.

Aim: To investigate the chemical constituents of the leaves and twigs of Securinega suffruticosa (Pall.) Rehd. Method: Column chromatographic methods were used to separate the chemical constituents whose structures were elucidated by means of physicochemical properties and spectral analysis. Result: Eleven compounds were isolated and identified as (-)-15β-ethoxy-14,15-dihydroviroallosecurinine (1), securinine (2), 14,15-dihydrosecurinine (3), 4-epiphyllanthine (4), Securitinine (5), viroallosecurinine (6), Securinol A (7), secu' amamine A (8), ent-phyllanthidine (9), (+)-aquilegiolide (10) and (+)-menisdaurilide (11), respectively. Conclusion: Compound 1 is a novel compound. Compounds 4, 8, 10 and 11 were isolated from Securinega suffruticosa for the first time.

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