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Sodium citrate

CAS# 68-04-2

Sodium citrate

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Sodium citrate

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Chemical Properties of Sodium citrate

Cas No. 68-04-2 SDF Download SDF
PubChem ID 6224 Appearance Powder
Formula C6H5Na3O7 M.Wt 258.07
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble to 3000 mM in water
Chemical Name 2-Hydroxy-1,2,3-propanenetricarboxylic acid trisodium salt dihydrate
SMILES C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Na+].[Na+].[Na+]
Standard InChIKey HRXKRNGNAMMEHJ-UHFFFAOYSA-K
Standard InChI InChI=1S/C6H8O7.3Na/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Sodium citrate

DescriptionCommonly used laboratory reagent

Sodium citrate Dilution Calculator

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Sodium citrate Molarity Calculator

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Preparing Stock Solutions of Sodium citrate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.8749 mL 19.3746 mL 38.7492 mL 77.4984 mL 96.8729 mL
5 mM 0.775 mL 3.8749 mL 7.7498 mL 15.4997 mL 19.3746 mL
10 mM 0.3875 mL 1.9375 mL 3.8749 mL 7.7498 mL 9.6873 mL
50 mM 0.0775 mL 0.3875 mL 0.775 mL 1.55 mL 1.9375 mL
100 mM 0.0387 mL 0.1937 mL 0.3875 mL 0.775 mL 0.9687 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Sodium citrate

A randomised controlled trial of sodium citrate spray for non-conductive olfactory disorders.[Pubmed:28339165]

Clin Otolaryngol. 2017 Dec;42(6):1295-1302.

OBJECTIVES: Previous research has suggested that Sodium citrate improves hyposmia by decreasing mucus calcium levels in the nose. This study aimed to confirm or refute this effect in a single application and assess potential side-effects. DESIGN: Study design was a randomised double-blind controlled trial of Sodium citrate nasal spray (intervention) vs sterile water (control). Fifty-five patients with non-conductive olfactory loss were randomised to receive the intervention or placebo. SETTING: Tertiary care clinic. MAIN OUTCOME MEASURES: The primary outcome measure was improvement in measured olfactory thresholds for phenyl ethyl alcohol (PEA) over 2 hours. Other outcome measures assessed were improvement in olfactory thresholds in 1-butanol, eucalyptol and acetic acid; number of responders with a clinically relevant response in each arm; and adverse effects. RESULTS: A significant effect was seen in the intervention arm for PEA and for 1-butanol and eucalyptol when compared to the control arm (P<.05); 32% of the intervention arm responded in terms of improved sensitivity towards some of the odours. Minor adverse effects noted included sore throat, nasal paraesthesia, slight rhinorrhoea and itching. The duration of effect of the citrate is transient, peaking at 30-60 minutes after application. CONCLUSIONS: Sodium citrate yields some potential as a treatment for non-conductive olfactory loss; however, these findings require corroboration in further clinical trials looking at longer term regular use of the spray as a viable therapeutic option for patients where it would be applied at frequent intervals such as before mealtimes.

Ethylenediaminetetraacetic Acid, Sodium Citrate, Heparin and Citrate Phosphate Dextrose-Adenine Anticoagulants Differentially Affect Cytokine mRNA Expression in Blood Leukocytes.[Pubmed:28164647]

Clin Lab. 2016 Jul 1;62(7):1371-1374.

BACKGROUND: The aim of this study is to determine whether and how the anticoagulant agents EDTA, Sodium citrate, and heparin present in vacutainers and CPDA located in transfusion bags modify peripheral blood cell behavior. METHODS: We compared the effect of four anticoagulants within an expression study quantifying mRNA by realtime PCR in 60 blood samples. RESULTS: We observed a significant increase of TNFalpha and CCL2 mRNA expression in leukocytes placed in EDTA anticoagulant compared to leukocytes collected with citrate or heparin (p

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