SulochrinCAS# 519-57-3 |
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| Cas No. | 519-57-3 | SDF | Download SDF |
| PubChem ID | 160505 | Appearance | Powder |
| Formula | C17H16O7 | M.Wt | 332.30 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | methyl 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoate | ||
| SMILES | CC1=CC(=C(C(=C1)O)C(=O)C2=C(C=C(C=C2C(=O)OC)O)OC)O | ||
| Standard InChIKey | YJRLSCDUYLRBIZ-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C17H16O7/c1-8-4-11(19)15(12(20)5-8)16(21)14-10(17(22)24-3)6-9(18)7-13(14)23-2/h4-7,18-20H,1-3H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The culture broth of an Aspergillus species.
| Description | 1. Sulochrin has an inhibitory activity to eosinophil degranulation. 2. Sulochrin can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotoxicity up to 50 uM. 3. Sulochrin shows antifungal and antibacterial activities. |
| Targets | HCV | Antifection |
Sulochrin Dilution Calculator
Sulochrin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.0093 mL | 15.0466 mL | 30.0933 mL | 60.1866 mL | 75.2332 mL |
| 5 mM | 0.6019 mL | 3.0093 mL | 6.0187 mL | 12.0373 mL | 15.0466 mL |
| 10 mM | 0.3009 mL | 1.5047 mL | 3.0093 mL | 6.0187 mL | 7.5233 mL |
| 50 mM | 0.0602 mL | 0.3009 mL | 0.6019 mL | 1.2037 mL | 1.5047 mL |
| 100 mM | 0.0301 mL | 0.1505 mL | 0.3009 mL | 0.6019 mL | 0.7523 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Effects of ortho-substituent groups of sulochrin on inhibitory activity to eosinophil degranulation.[Pubmed:10450959]
Bioorg Med Chem Lett. 1999 Jul 19;9(14):1945-8.
Sulochrin, a metabolite of fungi, has been shown to have an inhibitory activity to eosinophil degranulation. A series of Sulochrin derivatives substituted at ortho-positions to the 10-carbonyl group was examined the activity. The importance of alkylester at C-6 position and several chemical properties of substituted groups at ortho-positions to exhibit activity are described.
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