TUG 424CAS# 1082058-99-8 |
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Quality Control & MSDS
3D structure
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| Cas No. | 1082058-99-8 | SDF | Download SDF |
| PubChem ID | 25150014 | Appearance | Powder |
| Formula | C18H16O2 | M.Wt | 264.32 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in DMSO > 10 mM | ||
| Chemical Name | 3-[4-[2-(2-methylphenyl)ethynyl]phenyl]propanoic acid | ||
| SMILES | CC1=CC=CC=C1C#CC2=CC=C(C=C2)CCC(=O)O | ||
| Standard InChIKey | FODHWOBAQBTTFS-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C18H16O2/c1-14-4-2-3-5-17(14)12-10-15-6-8-16(9-7-15)11-13-18(19)20/h2-9H,11,13H2,1H3,(H,19,20) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Agonist of the free fatty acid receptor FFA1 (GPR40) (EC50 = 32 nM). Enhances glucose-stimulated insulin secretion in INS-1E cells at 100 nM. |
TUG 424 Dilution Calculator
TUG 424 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.7833 mL | 18.9165 mL | 37.8329 mL | 75.6659 mL | 94.5823 mL |
| 5 mM | 0.7567 mL | 3.7833 mL | 7.5666 mL | 15.1332 mL | 18.9165 mL |
| 10 mM | 0.3783 mL | 1.8916 mL | 3.7833 mL | 7.5666 mL | 9.4582 mL |
| 50 mM | 0.0757 mL | 0.3783 mL | 0.7567 mL | 1.5133 mL | 1.8916 mL |
| 100 mM | 0.0378 mL | 0.1892 mL | 0.3783 mL | 0.7567 mL | 0.9458 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity.
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