Home >> Research Area >>Natural Products>>Alkaloids>> Taberdivarine H

Taberdivarine H

CAS# 1662688-34-7

Taberdivarine H

Catalog No. BCN6958----Order now to get a substantial discount!

Product Name & Size Price Stock
Taberdivarine H: 5mg $1064 In Stock
Taberdivarine H: 10mg Please Inquire In Stock
Taberdivarine H: 20mg Please Inquire Please Inquire
Taberdivarine H: 50mg Please Inquire Please Inquire
Taberdivarine H: 100mg Please Inquire Please Inquire
Taberdivarine H: 200mg Please Inquire Please Inquire
Taberdivarine H: 500mg Please Inquire Please Inquire
Taberdivarine H: 1000mg Please Inquire Please Inquire

Quality Control of Taberdivarine H

Number of papers citing our products

Chemical structure

Taberdivarine H

3D structure

Chemical Properties of Taberdivarine H

Cas No. 1662688-34-7 SDF Download SDF
PubChem ID 134715098 Appearance Powder
Formula C20H22N2O2 M.Wt 322.41
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (13E,14S,16S,18R)-13-ethylidene-11-methyl-1-aza-11-azoniapentacyclo[12.3.1.02,7.08,17.011,16]octadeca-2,4,6,8(17)-tetraene-18-carboxylate
SMILES CC=C1C[N+]2(CCC3=C4C2CC1C(N4C5=CC=CC=C35)C(=O)[O-])C
Standard InChIKey MBYUFXAXLKULGV-SFQLIIISSA-N
Standard InChI InChI=1S/C20H22N2O2/c1-3-12-11-22(2)9-8-14-13-6-4-5-7-16(13)21-18(14)17(22)10-15(12)19(21)20(23)24/h3-7,15,17,19H,8-11H2,1-2H3/b12-3-/t15-,17-,19+,22?/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Taberdivarine H

The aerial parts of Tabernaemontana officinalis.

Biological Activity of Taberdivarine H

DescriptionTaberdivarine H is a natural product from Tabernaemontana officinalis.
In vitro

Cytotoxic indole alkaloids from Tabernaemontana officinalis.[Pubmed: 25687604 ]

Phytochemistry. 2015 Dec;120:46-52.


METHODS AND RESULTS:
Continued interest in cytotoxic alkaloids resulted in the isolation of 37 alkaloids including 29 known monoterpenoid indole alkaloids from the aerial parts of Tabernaemontana officinalis. Of the remaining 8 alkaloids, six were bisindole alkaloids named taberdivarine A, taberdivarine B, taberdivarine C, taberdivarine D, taberdivarine E, taberdivarine F (1-6) and the two were monomers named taberdivarine G and Taberdivarine H (7-8).
CONCLUSIONS:
Alkaloids 1 and 2 are voaphylline-vobasinyl type bisindole alkaloids, a structural type previously unknown, while 3-6 exhibited cytotoxicity against three human cancer cell lines HeLa, MCF-7, and SW480 with IC50 values ranging from 1.42 to 11.35 μM.

Taberdivarine H Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Taberdivarine H Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Taberdivarine H

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1016 mL 15.5082 mL 31.0164 mL 62.0328 mL 77.541 mL
5 mM 0.6203 mL 3.1016 mL 6.2033 mL 12.4066 mL 15.5082 mL
10 mM 0.3102 mL 1.5508 mL 3.1016 mL 6.2033 mL 7.7541 mL
50 mM 0.062 mL 0.3102 mL 0.6203 mL 1.2407 mL 1.5508 mL
100 mM 0.031 mL 0.1551 mL 0.3102 mL 0.6203 mL 0.7754 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Taberdivarine H

Cytotoxic indole alkaloids from Tabernaemontana officinalis.[Pubmed:25687604]

Phytochemistry. 2015 Dec;120:46-52.

Continued interest in cytotoxic alkaloids resulted in the isolation of 37 alkaloids including 29 known monoterpenoid indole alkaloids from the aerial parts of Tabernaemontana officinalis. Of the remaining 8 alkaloids, six were bisindole alkaloids named taberdivarines A-F (1-6) and the two were monomers named taberdivarines G and H (7-8). Alkaloids 1 and 2 are voaphylline-vobasinyl type bisindole alkaloids, a structural type previously unknown, while 3-6 exhibited cytotoxicity against three human cancer cell lines HeLa, MCF-7, and SW480 with IC50 values ranging from 1.42 to 11.35 muM.

Keywords:

Taberdivarine H,1662688-34-7,Natural Products, buy Taberdivarine H , Taberdivarine H supplier , purchase Taberdivarine H , Taberdivarine H cost , Taberdivarine H manufacturer , order Taberdivarine H , high purity Taberdivarine H

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: