4-Hydroxy-TeriflunomideMultiple sclerosis (MS) oral drug CAS# N/A |
Quality Control & MSDS
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| Cas No. | N/A | SDF | Download SDF |
| PubChem ID | 54684141 | Appearance | Powder |
| Formula | C12H9F3N2O3 | M.Wt | 286.21 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 100 mM in DMSO | ||
| Chemical Name | (Z)-2-cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide | ||
| SMILES | C1=CC(=CC=C1C(F)(F)F)NC(=O)C(=C(CO)O)C#N | ||
| Standard InChIKey | WHYQOFDUXDGMTM-KTKRTIGZSA-N | ||
| Standard InChI | InChI=1S/C12H9F3N2O3/c13-12(14,15)7-1-3-8(4-2-7)17-11(20)9(5-16)10(19)6-18/h1-4,18-19H,6H2,(H,17,20)/b10-9- | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Inhibitor of dihydroorotate dehydrogenase (Kd = 12 nM; Ki = 179 nM). Inhibits proliferation of mitogen- or cytokine-stimulated lymphoid cells in vitro by inhibiting cell cycle progression from G1 to S. Imunosuppressive agent. Active metabolite of leflunomide. |
4-Hydroxy-Teriflunomide Dilution Calculator
4-Hydroxy-Teriflunomide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.4939 mL | 17.4697 mL | 34.9394 mL | 69.8788 mL | 87.3485 mL |
| 5 mM | 0.6988 mL | 3.4939 mL | 6.9879 mL | 13.9758 mL | 17.4697 mL |
| 10 mM | 0.3494 mL | 1.747 mL | 3.4939 mL | 6.9879 mL | 8.7348 mL |
| 50 mM | 0.0699 mL | 0.3494 mL | 0.6988 mL | 1.3976 mL | 1.747 mL |
| 100 mM | 0.0349 mL | 0.1747 mL | 0.3494 mL | 0.6988 mL | 0.8735 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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