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Torachrysone 8-O-glucoside

CAS# 64032-49-1

Torachrysone 8-O-glucoside

Catalog No. BCN4181----Order now to get a substantial discount!

Product Name & Size Price Stock
Torachrysone 8-O-glucoside: 5mg $288 In Stock
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Torachrysone 8-O-glucoside: 200mg Please Inquire Please Inquire
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Quality Control of Torachrysone 8-O-glucoside

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Chemical structure

Torachrysone 8-O-glucoside

3D structure

Chemical Properties of Torachrysone 8-O-glucoside

Cas No. 64032-49-1 SDF Download SDF
PubChem ID 11972479 Appearance Yellow powder
Formula C20H24O9 M.Wt 408.4
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-[1-hydroxy-6-methoxy-3-methyl-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxynaphthalen-2-yl]ethanone
SMILES CC1=C(C(=C2C(=C1)C=C(C=C2OC3C(C(C(C(O3)CO)O)O)O)OC)O)C(=O)C
Standard InChIKey GHKWPHRULCFTBB-CZNQJBLBSA-N
Standard InChI InChI=1S/C20H24O9/c1-8-4-10-5-11(27-3)6-12(15(10)17(24)14(8)9(2)22)28-20-19(26)18(25)16(23)13(7-21)29-20/h4-6,13,16,18-21,23-26H,7H2,1-3H3/t13-,16-,18+,19-,20-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Torachrysone 8-O-glucoside

The rhizoma of Rheum officinale L.

Biological Activity of Torachrysone 8-O-glucoside

Description1. Torachryson-8-O-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes.
TargetsAntifection

Torachrysone 8-O-glucoside Dilution Calculator

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Torachrysone 8-O-glucoside Molarity Calculator

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Preparing Stock Solutions of Torachrysone 8-O-glucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4486 mL 12.2429 mL 24.4858 mL 48.9716 mL 61.2145 mL
5 mM 0.4897 mL 2.4486 mL 4.8972 mL 9.7943 mL 12.2429 mL
10 mM 0.2449 mL 1.2243 mL 2.4486 mL 4.8972 mL 6.1214 mL
50 mM 0.049 mL 0.2449 mL 0.4897 mL 0.9794 mL 1.2243 mL
100 mM 0.0245 mL 0.1224 mL 0.2449 mL 0.4897 mL 0.6121 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Torachrysone 8-O-glucoside

The screening of potential α-glucosidase inhibitors from the Polygonum multiflorum extract using ultrafiltration combined with liquid chromatography-tandem mass spectrometry

Anal. Methods-UK. 2014, 6(10):3353-9.

α-Glucosidase inhibitors have been used for the management of type 2 diabetes (T2DM) for a long time. The natural α-glucosidase inhibitors from Chinese herbal medicine have become an attractive therapeutic approach for treating T2DM due to their low toxicity. In this study, a new kind of in vitro α-glucosidase inhibition assay based on using maltose as the substrate was developed, and this new established method was used to determine the α-glucosidase inhibitory activities of Polygonum multiflorum and four anthraquinone compounds. As a result, Polygonum multiflorum showed 50% α-glucosidase inhibition at the concentration of 0.0032 mg mL−1 and four anthraquinone compounds including emodin, aloe-emodin, physcion and rhein showed strong α-glucosidase inhibitory activities with IC50 values ranging from 4.12 μM to 5.68 μM, respectively. Moreover, the centrifugal ultrafiltration with LC-ESI-MSn was used to screen and identify active α-glucosidase inhibitors from Polygonum multiflorum extract and nine small-molecule active compounds were successfully identified as potential α-glucosidase inhibitors. Five compounds belonged to the anthraquinone group including emodin, physcion, aloe-emodin, rhein and physcion-8-O-glucoside, while the others were catechin, resveratrol, 2,3,5,4′-tetrahydroxystilbene-2-O-glucoside and Torachrysone 8-O-glucoside.

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